SCOPe 2.08: Domain d1thga1: 1thg A:2-544

Lineage for d1thga1 (1thg A:2-544)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (43 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.17: Fungal lipases [53558] (5 proteins)

6. Protein Type-B carboxylesterase/lipase [53566] (4 species)

7. Species Fungus (Geotrichum candidum), ATCC 34614 [TaxId:27317] [53567] (1 PDB entry)

8. Domain d1thga1: 1thg A:2-544 [34763]
   Other proteins in same PDB: d1thga2
   complexed with nag, ndg
   has additional insertions and/or extensions that are not grouped together

Details for d1thga1

PDB Entry: 1thg, 1.8 Å

PDB Description: 1.8 angstroms refined structure of the lipase from geotrichum candidum

PDB Compounds: (A:) lipase 2

SCOPe Domain Sequences for d1thga1:

Sequence; same for both SEQRES and ATOM records:

>d1thga1 c.69.1.17 (A:2-544) Type-B carboxylesterase/lipase {Fungus (Geotrichum candidum), ATCC 34614 [TaxId: 27317]}
aptavlngnevisgvlegkvdtfkgipfadpplndlrfkhpqpftgsyqglkandfspac
mqldpgnsltlldkalglakvipeefrgplydmakgtvsmnedclylnvfrpagtkpdak
lpvmvwiyggafvygssaaypgnsyvkesinmgqpvvfvsinyrtgpfgflggdaitaeg
ntnaglhdqrkglewvsdnianfggdpdkvmifgesagamsvahqliayggdntyngkkl
fhsailqsggplpyhdsssvgpdisynrfaqyagcdtsasandtleclrsksssvlhdaq
nsydlkdlfgllpqflgfgprpdgniipdaayelfrsgryakvpyisgnqedegtafapv
alnatttphvkkwlqyifydaseasidrvlslypqtlsvgspfrtgilnaltpqfkrvaa
ilsdmlfqsprrvmlsatkdvnrwtylsthlhnlvpflgtfhgnelifqfnvnigpansy
lryfisfanhhdpnvgtnllqwdqytdegkemleihmtdnvmrtddyriegisnfetdvn
lyg

Timeline for d1thga1:

• d1thga1 first appeared (with stable ids) in SCOP 1.55, called d1thg__
  
• d1thga1 appears in SCOPe 2.07