SCOP 1.73: Domain d1e8ma2: 1e8m A:431-710

Lineage for d1e8ma2 (1e8m A:431-710)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (35 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.4: Prolyl oligopeptidase, C-terminal domain [53496] (1 protein)
   N-terminal domain is a 7-bladed beta-propeller

6. Protein Prolyl oligopeptidase, C-terminal domain [53497] (1 species)

7. Species Pig (Sus scrofa) [TaxId:9823] [53498] (16 PDB entries)

8. Domain d1e8ma2: 1e8m A:431-710 [34642]
   Other proteins in same PDB: d1e8ma1
   complexed with bzo, gly, gol, pro; mutant

Details for d1e8ma2

PDB Entry: 1e8m, 1.5 Å

PDB Description: prolyl oligopeptidase from porcine brain, mutant, complexed with inhibitor

PDB Compounds: (A:) prolyl endopeptidase

SCOP Domain Sequences for d1e8ma2:

Sequence; same for both SEQRES and ATOM records:

>d1e8ma2 c.69.1.4 (A:431-710) Prolyl oligopeptidase, C-terminal domain {Pig (Sus scrofa) [TaxId: 9823]}
dasdyqtvqifypskdgtkipmfivhkkgikldgshpaflygyggfnisitpnysvsrli
fvrhmggvlavanirgggeygetwhkggilankqncfddfqcaaeylikegytspkrlti
ngganggllvatcanqrpdlfgcviaqvgvmdmlkfhkytighawttdygcsdskqhfew
likysplhnvklpeaddiqypsmllltadhddrvvplhslkfiatlqyivgrsrkqnnpl
lihvdtkaghgagkptakvieevsdmfafiarclnidwip

Timeline for d1e8ma2:

• d1e8ma2 first appeared (with stable ids) in SCOP 1.55
  
• d1e8ma2 appears in SCOP 1.71
  
• d1e8ma2 appears in SCOP 1.75
  
• d1e8ma2 appears in the current release, SCOPe 2.08