SCOPe 2.07: Protein: CRISPR-associated endonuclease Cas9/Csn1, HNH domain

Root: SCOPe 2.07
Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
Fold d.4: His-Me finger endonucleases [54059] (1 superfamily)
core: (alpha)-beta-omega_loop-beta-alpha; embeded in larger different structures
Superfamily d.4.1: His-Me finger endonucleases [54060] (8 families)
common motif contains conserved histidine residue and metal-binding site
Family d.4.1.8: HNH domain from CRISPR-associated protein Cas9 [345970] (1 protein)
Homology to HNH nucleases noted in PubMed 21756346
Pfam PF13395
Protein CRISPR-associated endonuclease Cas9/Csn1, HNH domain [346090] (3 species)

Actinomyces naeslundii [TaxId:1115803] [346346] (1 PDB entry)
- Domain for 4ogc:
  - Domain d4ogca2: 4ogc A:513-673 [345372]
    Other proteins in same PDB: d4ogca1, d4ogca3, d4ogca4
    complexed with act, mg, mn, spd, zn
Staphylococcus aureus subsp. aureus [TaxId:46170] [346347] (1 PDB entry)
- Domain for 5axw:
  - Domain d5axwa2: 5axw A:484-630 [345542]
    Other proteins in same PDB: d5axwa1, d5axwa3, d5axwa4
    protein/DNA complex; protein/RNA complex; complexed with edo, na, po4
Streptococcus pyogenes [TaxId:301447] [346348] (2 PDB entries)
1. Domains for 4cmp:
  1. Domain d4cmpa2: 4cmp A:775-902 [345145]
    Other proteins in same PDB: d4cmpa1, d4cmpa3, d4cmpa4, d4cmpb1, d4cmpb2, d4cmpb4
    complexed with mg, so4
  2. Domain d4cmpb3: 4cmp B:773-902 [345150]
    Other proteins in same PDB: d4cmpa1, d4cmpa3, d4cmpa4, d4cmpb1, d4cmpb2, d4cmpb4
    automated match to d4cmpa2
    complexed with mg, so4
2. Domain for 4oo8:
  - Domain d4oo8a2: 4oo8 A:775-907 [345380]
    Other proteins in same PDB: d4oo8a1, d4oo8a3, d4oo8a4, d4oo8d1, d4oo8d2, d4oo8d3
    protein/DNA complex; protein/RNA complex

Timeline for Protein CRISPR-associated endonuclease Cas9/Csn1, HNH domain from d.4.1.8: HNH domain from CRISPR-associated protein Cas9:

Protein CRISPR-associated endonuclease Cas9/Csn1, HNH domain from d.4.1.8: HNH domain from CRISPR-associated protein Cas9 is new in SCOPe 2.07-stable
Protein CRISPR-associated endonuclease Cas9/Csn1, HNH domain from d.4.1.8: HNH domain from CRISPR-associated protein Cas9 appears in the current release, SCOPe 2.08