Lineage for Family e.8.1.8: Splicing factor Prp8 RT domain

  1. Root: SCOPe 2.07
  2. 2568173Class e: Multi-domain proteins (alpha and beta) [56572] (71 folds)
  3. 2571153Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
    divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members
  4. 2571154Superfamily e.8.1: DNA/RNA polymerases [56672] (8 families) (S)
    "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain
  5. 2572842Family e.8.1.8: Splicing factor Prp8 RT domain [345981] (2 proteins)
    Pfam PF10598, Pfam PF10597. Includes linker domain discussed in PubMed 23354046
    Homology to retroviral RT domains discussed in PubMed 21441348

Proteins:

  1. 2572843Pre-mRNA splicing factor 8, Prp8 / Spp42 [346115] (2 species)
    1. 2572844Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [346406] (1 PDB entry)
    2. 2572846Species Schizosaccharomyces pombe 972h- [TaxId:284812] [346407] (1 PDB entry)
  2. 2572848automated matches [346116] (1 species)
    not a true protein

More info for Family e.8.1.8: Splicing factor Prp8 RT domain

Timeline for Family e.8.1.8: Splicing factor Prp8 RT domain:

  • Family e.8.1.8: Splicing factor Prp8 RT domain is new in SCOPe 2.07-stable