Lineage for Family a.118.8.9: TPR-like repeats from PCI (proteasome / COP9 signalosome / eIF3) domains

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2332674Fold a.118: alpha-alpha superhelix [48370] (28 superfamilies)
    multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix
  4. 2333768Superfamily a.118.8: TPR-like [48452] (10 families) (S)
  5. 2334044Family a.118.8.9: TPR-like repeats from PCI (proteasome / COP9 signalosome / eIF3) domains [345951] (10 protein domains)
    N-terminal part of Pfam PF06272
    Described in PubMed 15180986 as 'HAM (HEAT analagous motif) domain'
    Probably homologous to TPR rather than HEAT, based on PubMed 15790418

Protein Domains:

  1. 2334045COP9 signalosome complex subunit 1 (CSN1), N-terminal domain [346031] (1 species)
  2. 2334051COP9 signalosome complex subunit 7 (CSN7), N-terminal domain [346032] (1 species)
  3. 2334054Eukaryotic translation initiation factor 3 subunit 12, eIF3k, N-terminal domain [346010] (1 species)
  4. 2334057Proteasome regulatory subunit Rpn12, N-terminal domain [346033] (1 species)
  5. 2334060Proteasome regulatory subunit Rpn3, N-terminal domain [346034] (1 species)
  6. 2334063Proteasome regulatory subunit Rpn5, N-terminal domain [346035] (1 species)
  7. 2334066Proteasome regulatory subunit Rpn6, N-terminal domain [346036] (2 species)
    1. 2334067Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [346198] (1 PDB entry)
    2. 2334069Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [346199] (2 PDB entries)
  8. 2334072Proteasome regulatory subunit Rpn7, N-terminal domain [346037] (1 species)
  9. 2334075Proteasome regulatory subunit Rpn9, N-terminal domain [346038] (1 species)
  10. 2334078automated matches [346039] (1 species)
    not a true protein

More info for Family a.118.8.9: TPR-like repeats from PCI (proteasome / COP9 signalosome / eIF3) domains

Timeline for Family a.118.8.9: TPR-like repeats from PCI (proteasome / COP9 signalosome / eIF3) domains: