Lineage for Fold e.80: CRISPR-associated endonuclease Cas9/Csn1, Protospace-adjacent motif (PAM)-interacting domain

  1. Root: SCOPe 2.07
  2. 2568173Class e: Multi-domain proteins (alpha and beta) [56572] (71 folds)
  3. 2575192Fold e.80: CRISPR-associated endonuclease Cas9/Csn1, Protospace-adjacent motif (PAM)-interacting domain [345893] (1 superfamily)
    N-terminal part is structurally divergent wedge domain; middle domain is homologous to DNA gyrase B and Topoisomerase II; C-terminal domain appears to be Cas9-specific

Superfamily:

More info for Fold e.80: CRISPR-associated endonuclease Cas9/Csn1, Protospace-adjacent motif (PAM)-interacting domain

Timeline for Fold e.80: CRISPR-associated endonuclease Cas9/Csn1, Protospace-adjacent motif (PAM)-interacting domain:

  • Fold e.80: CRISPR-associated endonuclease Cas9/Csn1, Protospace-adjacent motif (PAM)-interacting domain is new in SCOPe 2.07-stable