SCOP 1.55: Domain d1eve__: 1eve -

Lineage for d1eve__ (1eve -)

1. Root: SCOP 1.55

2. Class c: Alpha and beta proteins (a/b) [51349] (97 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (20 families)

5. Family c.69.1.1: Acetylcholinesterase-like [53475] (3 proteins)

6. Protein Acetylcholinesterase [53476] (5 species)

7. Species Electric ray (Torpedo californica) [53477] (28 PDB entries)

8. Domain d1eve__: 1eve - [34585]

Details for d1eve__

PDB Entry: 1eve, 2.5 Å

PDB Description: three dimensional structure of the anti-alzheimer drug, e2020 (aricept), complexed with its target acetylcholinesterase

SCOP Domain Sequences for d1eve__:

Sequence; same for both SEQRES and ATOM records:

>d1eve__ c.69.1.1 (-) Acetylcholinesterase {Electric ray (Torpedo californica)}
dhsellvntksgkvmgtrvpvlsshisaflgipfaeppvgnmrfrrpepkkpwsgvwnas
typnncqqyvdeqfpgfsgsemwnpnremsedclylniwvpsprpksttvmvwiygggfy
sgsstldvyngkylayteevvlvslsyrvgafgflalhgsqeapgnvglldqrmalqwvh
dniqffggdpktvtifgesaggasvgmhilspgsrdlfrrailqsgspncpwasvsvaeg
rrravelgrnlncnlnsdeelihclrekkpqelidvewnvlpfdsifrfsfvpvidgeff
ptslesmlnsgnfkktqillgvnkdegsffllygapgfskdseskisredfmsgvklsvp
handlgldavtlqytdwmddnngiknrdglddivgdhnvicplmhfvnkytkfgngtyly
ffnhrasnlvwpewmgvihgyeiefvfglplvkelnytaeeealsrrimhywatfaktgn
pnephsqeskwplfttkeqkfidlntepmkvhqrlrvqmcvfwnqflpkllnat

Timeline for d1eve__:

• d1eve__ appears in SCOP 1.57
  
• d1eve__ appears in the current release, SCOPe 2.08, called d1evea_