SCOPe 2.08: Domain d5o9zg_: 5o9z G:

Lineage for d5o9zg_ (5o9z G:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (28 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.8: TPR-like [48452] (11 families)

5. Family a.118.8.1: Tetratricopeptide repeat (TPR) [48453] (21 proteins)
   this is a repeat family; one repeat unit is 1zb1 A:166-231 found in domain

6. Protein Pre-mRNA splicing factor 6 [346027] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [346189] (1 PDB entry)

8. Domain d5o9zg_: 5o9z G: [345813]
   Other proteins in same PDB: d5o9ze1, d5o9ze2, d5o9zh1, d5o9zh2, d5o9zi_, d5o9zk_, d5o9zp_, d5o9zv_, d5o9zx_, d5o9zy_
   protein/RNA complex
   has additional insertions and/or extensions that are not grouped together

Details for d5o9zg_

PDB Entry: 5o9z

PDB Description: cryo-em structure of a pre-catalytic human spliceosome primed for activation (b complex)

PDB Compounds: (G:) Pre-mRNA-processing factor 6

SCOPe Domain Sequences for d5o9zg_:

Sequence, based on SEQRES records:

>d5o9zg_ a.118.8.1 (G:) Pre-mRNA splicing factor 6 {Human (Homo sapiens) [TaxId: 9606]}
kpflgmpaplgyvpglgrgatgfttrsdigpardandpvddrhappgkrtvgdqmkknqa
addddedlndtnydefngyagslfssgpyekddeeadaiyaaldkrmderrkerreqrek
eeiekyrmerpkiqqqfsdlkrklaevteeewlsipevgdarnkrqrnpryekltpvpds
ffakhlqtgenhtsvdprqtqfgglntpypgglntpypggmtpglmtpgtgeldmrkigq
arntlmdmrlsqvsdsvsgqtvvdpkgyltdlnsmipthggdindikkarlllksvretn
phhppawiasarleevtgklqvarnlimkgtemcpksedvwleaarlqpgdtakavvaqa
vrhlpqsvriyiraaeletdirakkrvlrkalehvpnsvrlwkaaveleepedarimlsr
aveccptsvelwlalarletyenarkvlnkareniptdrhiwitaakleeangntqmvek
iidraitslrangveinreqwiqdaeecdragsvatcqavmravigigieeedrkhtwme
dadscvahnalecaraiyayalqvfpskksvwlraayfeknhgtresleallqravahcp
kaevlwlmgakskwlagdvpaarsilalafqanpnseeiwlaavklesendeyerarrll
akarssaptarvfmksvklewvqdniraaqdlceealrhyedfpklwmmkgqieeqkemm
ekareaynqglkkcphstplwlllsrleekigqltraraileksrlknpknpglwlesvr
leyraglkniantlmakalqecpnsgilwseaiflearpqrrtksvdalkkcehdphvll
avaklfwsqrkitkarewfhrtvkidsdlgdawaffykfelqhgteeqqeevrkrcesae
prhgelwcavskdianwqkkigdilrlvagrikntf

Sequence, based on observed residues (ATOM records):

>d5o9zg_ a.118.8.1 (G:) Pre-mRNA splicing factor 6 {Human (Homo sapiens) [TaxId: 9606]}
kpflgmpaplgyvpglgrgatkddeeadaiyaaldkrmderrkerreqrekeeiekyrme
rpkiqqqfsdlkrklaevteeewlsipevgdarnkrqrnpryekltpvpdsffakhlqtg
enhtsvdprqtqfggyltdlnsmipthggdindikkarlllksvretnphhppawiasar
leevtgklqvarnlimkgtemcpksedvwleaarlqpgdtakavvaqavrhlpqsvriyi
raaeletdirakkrvlrkalehvpnsvrlwkaaveleepedarimlsraveccptsvelw
lalarletyenarkvlnkareniptdrhiwitaakleeangntqmvekiidraitslran
gveinreqwiqdaeecdragsvatcqavmravigigieeedrkhtwmedadscvahnale
caraiyayalqvfpskksvwlraayfeknhgtresleallqravahcpkaevlwlmgaks
kwlagdvpaarsilalafqanpnseeiwlaavklesendeyerarrllakarssaptarv
fmksvklewvqdniraaqdlceealrhyedfpklwmmkgqieeqkemmekareaynqglk
kcphstplwlllsrleekigqltraraileksrlknpknpglwlesvrleyraglknian
tlmakalqecpnsgilwseaiflearpqrrtksvdalkkcehdphvllavaklfwsqrki
tkarewfhrtvkidsdlgdawaffykfelqhgteeqqeevrkrcesaeprhgelwcavsk
dianwqkkigdilrlvagrikntf

Timeline for d5o9zg_:

• d5o9zg_ first appeared in SCOPe 2.07