SCOPe 2.08: Domain d5o9ze2: 5o9z E:540-675

Lineage for d5o9ze2 (5o9z E:540-675)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.58: Ferredoxin-like [54861] (62 superfamilies)
   alpha+beta sandwich with antiparallel beta-sheet; (beta-alpha-beta)x2

4. Superfamily d.58.10: Acylphosphatase/BLUF domain-like [54975] (4 families)

5. Family d.58.10.3: Spliceosomal U4/U6 small nuclear ribonucleoprotein Prp3 C-terminal domain-like [345972] (1 protein)
   Pfam PF06544; relationship to BLUF domain discussed in PubMed 26161500

6. Protein Spliceosomal U4/U6 small nuclear ribonucleoprotein Prp3 [346095] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [346361] (1 PDB entry)

8. Domain d5o9ze2: 5o9z E:540-675 [345812]
   Other proteins in same PDB: d5o9ze1, d5o9zg_, d5o9zh1, d5o9zh2, d5o9zi_, d5o9zk_, d5o9zp_, d5o9zv_, d5o9zx_, d5o9zy_
   protein/RNA complex

Details for d5o9ze2

PDB Entry: 5o9z

PDB Description: cryo-em structure of a pre-catalytic human spliceosome primed for activation (b complex)

PDB Compounds: (E:) U4/U6 small nuclear ribonucleoprotein Prp3

SCOPe Domain Sequences for d5o9ze2:

Sequence, based on SEQRES records:

>d5o9ze2 d.58.10.3 (E:540-675) Spliceosomal U4/U6 small nuclear ribonucleoprotein Prp3 {Human (Homo sapiens) [TaxId: 9606]}
gvhisvyrvrnlsnpakkfkieanagqlyltgvvvlhkdvnvvvveggpkaqkkfkrlml
hrikwdeqtsntkgdddeesdeeavkktnkcvlvwegtakdrsfgemkfkqcptenmare
hfkkhgaehywdlals

Sequence, based on observed residues (ATOM records):

>d5o9ze2 d.58.10.3 (E:540-675) Spliceosomal U4/U6 small nuclear ribonucleoprotein Prp3 {Human (Homo sapiens) [TaxId: 9606]}
gvhisvyrvrnlsnpakkfkieanagqlyltgvvvlhkdvnvvvveggpkaqkkfkrlml
hrikavkktnkcvlvwegtakdrsfgemkfkqcptenmarehfkkhgaehywdlals

Timeline for d5o9ze2:

• d5o9ze2 first appeared in SCOPe 2.07