SCOPe 2.08: Domain d4c3hm_: 4c3h M:

Lineage for d4c3hm_ (4c3h M:)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.65: triple barrel [50915] (1 superfamily)
   dimer of two non-identical subunits; forms two similar barrels, n=8, S=10 each, that are fused together with the formation of third barrel, n=6, S=8

4. Superfamily b.65.1: Rap30/74 interaction domain-like [50916] (3 families)

5. Family b.65.1.2: RNA polymerase I A49/34.5, interaction domains [345965] (3 proteins)
   Homology with TFIIF discussed in PubMed 20797630

6. Protein RNA polymerase I subunit A49, interaction domain [346058] (2 species)
   N-terminal part of Pfam PF06870

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [346252] (2 PDB entries)

8. Domain d4c3hm_: 4c3h M: [345102]
   Other proteins in same PDB: d4c3ha_, d4c3hb_, d4c3hc1, d4c3hc2, d4c3hd_, d4c3he1, d4c3he2, d4c3hf_, d4c3hg1, d4c3hg2, d4c3hh_, d4c3hi1, d4c3hi2, d4c3hj_, d4c3hk_, d4c3hl_, d4c3hn_
   complexed with zn

Details for d4c3hm_

PDB Entry: 4c3h, 3.27 Å

PDB Description: Structure of 14-subunit RNA polymerase I at 3.27 A resolution, crystal form C2-93

PDB Compounds: (M:) DNA-directed RNA polymerase I subunit RPA49

SCOPe Domain Sequences for d4c3hm_:

Sequence, based on SEQRES records:

>d4c3hm_ b.65.1.2 (M:) RNA polymerase I subunit A49, interaction domain {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
seieiesvqdqpsvavgsffkgfrapsdttfdlykkkksekdefvlhgenerleyegytd
sssqasnqyvvglfnpekksiqlykapvlvskvvskssknlrgpkik

Sequence, based on observed residues (ATOM records):

>d4c3hm_ b.65.1.2 (M:) RNA polymerase I subunit A49, interaction domain {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
seieiesvqdqpsvavgsffkgfrapsdttfdlykkkekdefvlhgenerleyegytdss
sqasnqyvvglfnpekksiqlykapvlvskvvskssknlrgpkik

Timeline for d4c3hm_:

• d4c3hm_ first appeared in SCOPe 2.07