SCOPe 2.08: Domain d4c3ha_: 4c3h A:

Lineage for d4c3ha_ (4c3h A:)

1. Root: SCOPe 2.08

2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)

3. Fold e.29: beta and beta-prime subunits of DNA dependent RNA-polymerase [64483] (1 superfamily)
   Multidomain subunits of complex domain organization

4. Superfamily e.29.1: beta and beta-prime subunits of DNA dependent RNA-polymerase [64484] (3 families)
   The catalytic site is formed by the association of two double-psi beta-barrel domains, one from each subunit

5. Family e.29.1.2: RNA-polymerase beta-prime [64490] (4 proteins)

6. Protein RNA polymerase I subunit A190 [346118] (1 species)

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [346415] (2 PDB entries)

8. Domain d4c3ha_: 4c3h A: [345086]
   Other proteins in same PDB: d4c3hb_, d4c3hc1, d4c3hc2, d4c3hd_, d4c3he1, d4c3he2, d4c3hf_, d4c3hg1, d4c3hg2, d4c3hh_, d4c3hi1, d4c3hi2, d4c3hj_, d4c3hk_, d4c3hl_, d4c3hm_, d4c3hn_
   complexed with zn

Details for d4c3ha_

PDB Entry: 4c3h, 3.27 Å

PDB Description: Structure of 14-subunit RNA polymerase I at 3.27 A resolution, crystal form C2-93

PDB Compounds: (A:) DNA-directed RNA polymerase I subunit rpa190

SCOPe Domain Sequences for d4c3ha_:

Sequence, based on SEQRES records:

>d4c3ha_ e.29.1.2 (A:) RNA polymerase I subunit A190 {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
mdiskpvgseitsvdfgiltakeirnlsakqitnptvldnlghpvsgglydlalgaflrn
lcstcgldekfcpghqghielpvpcynplffnqlyiylrasclfchhfrlksvevhryac
klrllqyglidesykldeitlgslnssmytddeaiednedemdgegskqskdisstllne
lkskrseyvdmaiakalsdgrttergsftatvnderkklvhefhkkllsrgkcdncgmfs
pkfrkdgftkifetalnekqitnnrvkgfirqdmikkqkqakkldgsneasandeesfdv
grnpttrpktgstyilstevknildtvfrkeqcvlqyvfhsrpnlsrklvkadsffmdvl
vvpptrfrlpsklgeevhensqnqllskvlttsllirdlnddlsklqkdkvsledrrvif
srlmnafvtiqndvnafidstkaqgrtsgkvpipgvkqalekkeglfrkhmmgkrvnyaa
rsvispdpnietneigvppvfavkltypepvtayniaelrqavingpdkwpgatqiqned
gslvsligmsveqrkalanqlltpssnvsthtlnkkvyrhiknrdvvlmnrqptlhkasm
mghkvrvlpnektlrlhyantgaynadfdgdemnmhfpqnenaraealnlantdsqyltp
tsgspvrgliqdhisagvwltskdsfftreqyqqyiygcirpedghttrskivtlpptif
kpyplwtgkqiittvllnvtppdmpginlisknkikneywgkgslenevlfkdgallcgi
ldksqygaskygivhslhevygpevaakvlsvlgrlftnyitataftcgmddlrltaegn
kwrtdilktsvdtgreaaaevtnldkdtpaddpellkrlqeilrdnnksgildavtsskv
naitsqvvskcvpdgtmkkfpcnsmqamalsgakgsnvnvsqimcllgqqalegrrvpvm
vsgktlpsfkpyetdamaggyvkgrfysgikpqeyyfhcmagreglidtavktsrsgylq
rcltkqlegvhvsydnsirdadgtlvqfmyggdaiditkeshmtqfefcldnyyallkky
npsaliehldvesalkyskktlkyrkkhskephykqsvkydpvlakynpakylgsvsenf
qdklesfldknsklfkssdgvnekkfralmqlkymrslinpgeavgiiasqsvgepstqm
tlntfhfaghgaanvtlgiprlreivmtasaaiktpqmtlpiwndvsdeqadtfcksisk
vllsevidkvivtettgtsntaggnaarsyvihmrffdnneyseeydvskeelqnvisnq
fihlleaaivkeikkqkrttgpdigvavprlqtdvansssnskrleedndeeqshkktkq
avsydepdedeietmreaekssdeegidsdkesdsdsededvdmneqinksiveannnmn
kvqrdrqsaiishhrfitkynfddesgkwcefklelaadtekllmvniveeicrksiirq
iphidrcvhpepengkrvlvtegvnfqamwdqeafidvdgitsndvaavlktygveaarn
tivneinnvfsryaisvsfrhldliadmmtrqgtylafnrqgmetstssfmkmsyettcq
fltkavldnereqldspsarivvgklnnvgtgsfdvlakvpna

Sequence, based on observed residues (ATOM records):

>d4c3ha_ e.29.1.2 (A:) RNA polymerase I subunit A190 {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
mdiskpvgseitsvdfgiltakeirnlsakqitnptvldnlghpvsgglydlalgaflrn
lcstcgldekfcpghqghielpvpcynplffnqlyiylrasclfchhfrlksvevhryac
klrllqyglidesykldeitldisstllnelkskrseyvdmaiakalsdgrttergsfta
tvnderkklvhefhkkllsrgkcdncgmfspkfrkdgftkifetalnekqitnnrvkgfi
rqdmistyilstevknildtvfrkeqcvlqyvfhsrpnlsrklvkadsffmdvlvvpptr
frlpsklgeevhensqnqllskvlttsllirdlnddlsklkvsledrrvifsrlmnafvt
iqndvnafidstkaqgrtvpipgvkqalekkeglfrkhmmgkrvnyaarsvispdpniet
neigvppvfavkltypepvtayniaelrqavingpdkwpgatqiqnedgslvsligmsve
qrkalanqlltpssnvsthtlnkkvyrhiknrdvvlmnrqptlhkasmmghkvrvlpnek
tlrlhyantgaynadfdgdemnmhfpqnenaraealnlantdsqyltptsgspvrgliqd
hisagvwltskdsfftreqyqqyiygcirpedghttrskivtlpptifkpyplwtgkqii
ttvllnvtppdmpginlisknkikneywgkgslenevlfkdgallcgildksqygaskyg
ivhslhevygpevaakvlsvlgrlftnyitataftcgmddlrltaegnkwrtdilktsvd
tgreaaaevtnldkdtpaddpellkrlqeilrdnnksgildavtsskvnaitsqvvskcv
pdgtmkkfpcnsmqamalsgakgsnvnvsqimcllgqqalegrrvpvmvsgktlpsfkpy
etdamaggyvkgrfysgikpqeyyfhcmagreglidtavktsrsgylqrcltkqlegvhv
sydnsirdadgtlvqfmyggdaiditkeshmtqfefcldnyyallkkynpsaliehldve
salkyskktlkyrkkhskephykqsvkydpvlakynpakylgsvsenfqdklesfldkns
kgvnekkfralmqlkymrslinpgeavgiiasqsvgepstqmtlntfnvtlgiprlreiv
mtasaaiktpqmtlpiwndvsdeqadtfcksiskvllsevidkvivtettgtarsyvihm
rffdnneyseeydvskeelqnvisnqfihlleaaivkeikkqkrttgpdigvavprlqns
krleedndeeqshkktkqavsydepdedeietmreaenmnkvqrdrqsaiishhrfitky
nfddesgkwcefklelaadtekllmvniveeicrksiirqiphidrcvhpepengkrvlv
tegvnfqamwdqeafidvdgitsndvaavlktygveaarntivneinnvfsryaisvsfr
hldliadmmtrqgtylafnrqgmetstssfmkmsyettcqfltkavldnereqldspsar
ivvgklnnvgtgsfdvlakvpna

Timeline for d4c3ha_:

• d4c3ha_ first appeared in SCOPe 2.07