Lineage for d2wx2a_ (2wx2 A:)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2330957Fold a.104: Cytochrome P450 [48263] (1 superfamily)
    multihelical
  4. 2330958Superfamily a.104.1: Cytochrome P450 [48264] (2 families) (S)
  5. 2331668Family a.104.1.0: automated matches [191509] (1 protein)
    not a true family
  6. 2331669Protein automated matches [190847] (73 species)
    not a true protein
  7. 2332286Species Trypanosoma cruzi [TaxId:5693] [196511] (19 PDB entries)
  8. 2332291Domain d2wx2a_: 2wx2 A: [344671]
    Other proteins in same PDB: d2wx2b2
    automated match to d4uhia_
    complexed with hem, tpf

Details for d2wx2a_

PDB Entry: 2wx2 (more details), 2.27 Å

PDB Description: x-ray structure of cyp51 from the human pathogen trypanosoma cruzi in complex with fluconazole
PDB Compounds: (A:) lanosterol 14-alpha-demethylase

SCOPe Domain Sequences for d2wx2a_:

Sequence, based on SEQRES records: (download)

>d2wx2a_ a.104.1.0 (A:) automated matches {Trypanosoma cruzi [TaxId: 5693]}
ttrptdppvypvtvpflghivqfgknplefmqrckrdlksgvftisiggqrvtivgdphe
hsrffsprneilsprevytimtpvfgegvayaapyprmreqlnflaeeltiakfqnfvpa
iqhevrkfmaenwkedegvinlledcgamiintacqclfgedlrkrlnarhfaqllskme
sslipaavfmpwllrlplpqsarcrearaelqkilgeiivarekeeaskdnntsdllggl
lkavyrdgtrmslhevcgmivaamfagqhtstittswsmlhlmhpknkkwldklhkeide
fpaqlnydnvmdempfaercvresirrdppllmvmrmvkaevkvgsyvvpkgdiiacspl
lshhdeeafpnprlwdperdekvdgafigfgagvhkcigqkfallqvktilatafreydf
qllrdevpdpdyhtmvvgptlnqclvkytrkk

Sequence, based on observed residues (ATOM records): (download)

>d2wx2a_ a.104.1.0 (A:) automated matches {Trypanosoma cruzi [TaxId: 5693]}
ttrptdppvypvtvpflghivqfgknplefmqrckrdlksgvftisiggqrvtivgdphe
hsrffsprneilsprevytimtpvfgegvayaapyprmreqlnflaeeltiakfqnfvpa
iqhevrkfmaenwkedegvinlledcgamiintacqclfgedlrkrlnarhfaqllskme
sslipaavfmpwllrlplprcrearaelqkilgeiivarekesdllggllkavyrdgtrm
slhevcgmivaamfagqhtstittswsmlhlmhpknkkwldklhkeidefpaqlnydnvm
dempfaercvresirrdppllmvmrmvkaevkvgsyvvpkgdiiacspllshhdeeafpn
prlwdperdekvdgafigfgagvhkcigqkfallqvktilatafreydfqllrdevpdpd
yhtmvvgptlnqclvkytrkk

SCOPe Domain Coordinates for d2wx2a_:

Click to download the PDB-style file with coordinates for d2wx2a_.
(The format of our PDB-style files is described here.)

Timeline for d2wx2a_:

  • d2wx2a_ is new in SCOPe 2.07-stable