Lineage for d2gk6a3 (2gk6 A:703-911)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2446887Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. 2446888Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families) (S)
    division into families based on beta-sheet topologies
  5. 2451114Family c.37.1.19: Tandem AAA-ATPase domain [81268] (27 proteins)
    duplication: tandem repeat of two RecA-like (AAA) domains
  6. 2451338Protein Upf1 [346071] (1 species)
    first domain includes small helical insert subdomain
  7. 2451339Species Human (Homo sapiens) [TaxId:9606] [346290] (3 PDB entries)
  8. 2451341Domain d2gk6a3: 2gk6 A:703-911 [344575]
    Other proteins in same PDB: d2gk6a2, d2gk6a4, d2gk6b2, d2gk6b4
    automated match to d2gjka2
    complexed with adp, mg, po4

Details for d2gk6a3

PDB Entry: 2gk6 (more details), 2.4 Å

PDB Description: Structural and Functional insights into the human Upf1 helicase core
PDB Compounds: (A:) Regulator of nonsense transcripts 1

SCOPe Domain Sequences for d2gk6a3:

Sequence, based on SEQRES records: (download)

>d2gk6a3 c.37.1.19 (A:703-911) Upf1 {Human (Homo sapiens) [TaxId: 9606]}
rmhpalsafpsnifyegslqngvtaadrvkkgfdfqwpqpdkpmffyvtqgqeeiassgt
sylnrteaanvekittkllkagakpdqigiitpyegqrsylvqymqfsgslhtklyqeve
iasvdafqgrekdfiilscvranehqgigflndprrlnvaltrarygviivgnpkalskq
plwnhllnyykeqkvlvegplnnlreslm

Sequence, based on observed residues (ATOM records): (download)

>d2gk6a3 c.37.1.19 (A:703-911) Upf1 {Human (Homo sapiens) [TaxId: 9606]}
rmhpalsafpsnifyegslqngvtaadrvkkgfdfqwpqpdkpmffyvtqgqeeiassgt
sylnrteaanvekittkllkagakpdqigiitpyegqrsylvqymqfsgslhtklyqeve
iasvdafqgrekdfiilscvrigflndprrlnvaltrarygviivgnpkalskqplwnhl
lnyykeqkvlvegplnnlreslm

SCOPe Domain Coordinates for d2gk6a3:

Click to download the PDB-style file with coordinates for d2gk6a3.
(The format of our PDB-style files is described here.)

Timeline for d2gk6a3: