Lineage for d5wmxb_ (5wmx B:)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2343809Fold a.266: Indolic compounds 2,3-dioxygenase-like [140958] (1 superfamily)
    multihelical; bundle, contains interrupted helices
  4. 2343810Superfamily a.266.1: Indolic compounds 2,3-dioxygenase-like [140959] (3 families) (S)
    contains heme-dependent enzymes
  5. 2343820Family a.266.1.2: Indoleamine 2,3-dioxygenase-like [140963] (3 protein domains)
    Pfam PF01231; contains extra N-terminal all-alpha subdomain of similar fold to the GST C-terminal domain (47615)
  6. 2343830Protein automated matches [190585] (2 species)
    not a true protein
  7. 2343831Species Human (Homo sapiens) [TaxId:9606] [187592] (21 PDB entries)
  8. 2343848Domain d5wmxb_: 5wmx B: [342606]
    automated match to d4u72b_
    complexed with cyn, hem, trp, zcw

Details for d5wmxb_

PDB Entry: 5wmx (more details), 2.69 Å

PDB Description: structural insights into substrate and inhibitor binding sites in human indoleamine 2,3-dioxygenase 1
PDB Compounds: (B:) Indoleamine 2,3-dioxygenase 1

SCOPe Domain Sequences for d5wmxb_:

Sequence, based on SEQRES records: (download)

>d5wmxb_ a.266.1.2 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
keyhideevgfalpnpqenlpdfyndwmfiakhlpdliesgqlrerveklnmlsidhltd
hksqrlarlvlgcitmayvwgkghgdvrkvlprniavpycqlskklelppilvyadcvla
nwkkkdpnkpltyenmdvlfsfrdgdcskgfflvsllveiaaasaikviptvfkamqmqe
rdtllkalleiasclekalqvfhqihdhvnpkaffsvlriylsgwkgnpqlsdglvyegf
wedpkefaggsagqssvgqcfdvllgiqqtaggghaaqflqdmrrymppahrnflcsles
npsvrefvlskgdaglreaydacvkalvslrsyhlqivtkyilipasqqpkenktsedps
kleakgtggtdlmnflktvrstteksllkeg

Sequence, based on observed residues (ATOM records): (download)

>d5wmxb_ a.266.1.2 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
keyhideevgfalpnpqenlpdfyndwmfiakhlpdliesgqlrerveklnmlsidhltd
hksqrlarlvlgcitmayvwgkghgdvrkvlprniavpycqlskklelppilvyadcvla
nwkkkdpnkpltyenmdvlfsfrdgdcskgfflvsllveiaaasaikviptvfkamqmqe
rdtllkalleiasclekalqvfhqihdhvnpkaffsvlriylsgwkgnpqlsdglvyegf
wedpkefaggsagqssvgqcfdvllgiqqtaghaaqflqdmrrymppahrnflcslesnp
svrefvlskgdaglreaydacvkalvslrsyhlqivtkyilipasqqpleakgtggtdlm
nflktvrstteksllkeg

SCOPe Domain Coordinates for d5wmxb_:

Click to download the PDB-style file with coordinates for d5wmxb_.
(The format of our PDB-style files is described here.)

Timeline for d5wmxb_: