Lineage for d5wn8b_ (5wn8 B:)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2343809Fold a.266: Indolic compounds 2,3-dioxygenase-like [140958] (1 superfamily)
    multihelical; bundle, contains interrupted helices
  4. 2343810Superfamily a.266.1: Indolic compounds 2,3-dioxygenase-like [140959] (3 families) (S)
    contains heme-dependent enzymes
  5. 2343820Family a.266.1.2: Indoleamine 2,3-dioxygenase-like [140963] (3 protein domains)
    Pfam PF01231; contains extra N-terminal all-alpha subdomain of similar fold to the GST C-terminal domain (47615)
  6. 2343830Protein automated matches [190585] (2 species)
    not a true protein
  7. 2343831Species Human (Homo sapiens) [TaxId:9606] [187592] (21 PDB entries)
  8. 2343844Domain d5wn8b_: 5wn8 B: [342514]
    automated match to d4u72b_
    complexed with bbj, hem

Details for d5wn8b_

PDB Entry: 5wn8 (more details), 2.5 Å

PDB Description: structural insights into substrate and inhibitor binding sites in human indoleamine 2,3-dioxygenase 1
PDB Compounds: (B:) Indoleamine 2,3-dioxygenase 1

SCOPe Domain Sequences for d5wn8b_:

Sequence, based on SEQRES records: (download)

>d5wn8b_ a.266.1.2 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
keyhideevgfalpnpqenlpdfyndwmfiakhlpdliesgqlrerveklnmlsidhltd
hksqrlarlvlgcitmayvwgkghgdvrkvlprniavpycqlskklelppilvyadcvla
nwkkkdpnkpltyenmdvlfsfrdgdcskgfflvsllveiaaasaikviptvfkamqmqe
rdtllkalleiasclekalqvfhqihdhvnpkaffsvlriylsgwkgnpqlsdglvyegf
wedpkefaggsagqssvfqcfdvllgiqqtaggghaaqflqdmrrymppahrnflcsles
npsvrefvlskgdaglreaydacvkalvslrsyhlqivtkyilipasqqpkenktsedps
kleakgtggtdlmnflktvrstteksllke

Sequence, based on observed residues (ATOM records): (download)

>d5wn8b_ a.266.1.2 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
keyhideevgfalpnpqenlpdfyndwmfiakhlpdliesgqlrerveklnmlsidhltd
hksqrlarlvlgcitmayvwgkghgdvrkvlprniavpycqlskklelppilvyadcvla
nwkkkdpnkpltyenmdvlfsfrdgdcskgfflvsllveiaaasaikviptvfkamqmqe
rdtllkalleiasclekalqvfhqihdhvnpkaffsvlriylsgwkgnpqlsdglvyegf
wedpkefaggsagqssvfqcfdvllgiqqtaggghaaqflqdmrrymppahrnflcsles
npsvrefvlskgdaglreaydacvkalvslrsyhlqivtkyilipasqgtdlmnflktvr
stteksllke

SCOPe Domain Coordinates for d5wn8b_:

Click to download the PDB-style file with coordinates for d5wn8b_.
(The format of our PDB-style files is described here.)

Timeline for d5wn8b_: