SCOPe 2.08: Domain d5wmwa_: 5wmw A:

Lineage for d5wmwa_ (5wmw A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.266: Indolic compounds 2,3-dioxygenase-like [140958] (1 superfamily)
   multihelical; bundle, contains interrupted helices

4. Superfamily a.266.1: Indolic compounds 2,3-dioxygenase-like [140959] (3 families)
   contains heme-dependent enzymes

5. Family a.266.1.2: Indoleamine 2,3-dioxygenase-like [140963] (3 proteins)
   Pfam PF01231; contains extra N-terminal all-alpha subdomain of similar fold to the GST C-terminal domain (47615)

6. Protein automated matches [190585] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187592] (52 PDB entries)

8. Domain d5wmwa_: 5wmw A: [342500]
   automated match to d4u72b_
   complexed with cyn, hem, trp

Details for d5wmwa_

PDB Entry: 5wmw, 3.03 Å

PDB Description: structural insights into substrate and inhibitor binding sites in human indoleamine 2,3-dioxygenase 1

PDB Compounds: (A:) Indoleamine 2,3-dioxygenase 1

SCOPe Domain Sequences for d5wmwa_:

Sequence, based on SEQRES records:

>d5wmwa_ a.266.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
skeyhideevgfalpnpqenlpdfyndwmfiakhlpdliesgqlrerveklnmlsidhlt
dhksqrlarlvlgcitmayvwgkghgdvrkvlprniavpycqlskklelppilvyadcvl
anwkkkdpnkpltyenmdvlfsfrdgdcskgfflvsllveiaaasaikviptvfkamqmq
erdtllkalleiasclekalqvfhqihdhvnpkaffsvlriylsgwkgnpqlsdglvyeg
fwedpkefaggsagqssvgqcfdvllgiqqtaggghaaqflqdmrrymppahrnflcsle
snpsvrefvlskgdaglreaydacvkalvslrsyhlqivtkyilipasqqpkenktsedp
skleakgtggtdlmnflktvrstteksllk

Sequence, based on observed residues (ATOM records):

>d5wmwa_ a.266.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
skeyhideevgfalpnpqenlpdfyndwmfiakhlpdliesgqlrerveklnmlsidhlt
dhksqrlarlvlgcitmayvwgkghgdvrkvlprniavpycqlskklelppilvyadcvl
anwkkkdpnkpltyenmdvlfsfrdgdcskgfflvsllveiaaasaikviptvfkamqmq
erdtllkalleiasclekalqvfhqihdhvnpkaffsvlriylsgwkgnpqlsdglvyeg
fwedpkefaggsagqssvgqcfdvllgiqqtaggghaaqflqdmrrymppahrnflcsle
snpsvrefvlskgdaglreaydacvkalvslrsyhlqivtkyilipasqqpkleakgtgg
tdlmnflktvrstteksllk

Timeline for d5wmwa_:

• d5wmwa_ first appeared in SCOPe 2.06
  
• d5wmwa_ appears in SCOPe 2.07