Lineage for d6b3sk1 (6b3s K:1-107)

  1. Root: SCOPe 2.07
  2. 2344607Class b: All beta proteins [48724] (178 folds)
  3. 2344608Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2344609Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2355236Family b.1.1.0: automated matches [191470] (1 protein)
    not a true family
  6. 2355237Protein automated matches [190740] (25 species)
    not a true protein
  7. 2355363Species Human (Homo sapiens) [TaxId:9606] [187920] (1236 PDB entries)
  8. 2357213Domain d6b3sk1: 6b3s K:1-107 [342257]
    Other proteins in same PDB: d6b3sa1, d6b3sa2, d6b3sb1, d6b3sb2, d6b3sb3, d6b3se1, d6b3se2, d6b3se3, d6b3si1, d6b3si2, d6b3si3
    automated match to d3b2ud1
    complexed with bma, man, nag

Details for d6b3sk1

PDB Entry: 6b3s (more details), 2.8 Å

PDB Description: crystal structure of the fab fragment of necitumumab (fab11f8) in complex with domain iii from a cetuximab resistant variant of egfr (segfrd3-s468r)
PDB Compounds: (K:) Necitumumab Fab Light chain

SCOPe Domain Sequences for d6b3sk1:

Sequence; same for both SEQRES and ATOM records: (download)

>d6b3sk1 b.1.1.0 (K:1-107) automated matches {Human (Homo sapiens) [TaxId: 9606]}
eivmtqspatlslspgeratlscrasqsvssylawyqqkpgqaprlliydasnratgipa
rfsgsgsgtdftltisslepedfavyychqygstpltfgggtkaeik

SCOPe Domain Coordinates for d6b3sk1:

Click to download the PDB-style file with coordinates for d6b3sk1.
(The format of our PDB-style files is described here.)

Timeline for d6b3sk1: