Lineage for d6b3si2 (6b3s I:481-502)

  1. Root: SCOPe 2.07
  2. 2581248Class g: Small proteins [56992] (98 folds)
  3. 2581531Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
    disulfide-bound fold; contains beta-hairpin with two adjacent disulfides
  4. 2582446Superfamily g.3.9: Growth factor receptor domain [57184] (2 families) (S)
  5. 2582517Family g.3.9.0: automated matches [232406] (1 protein)
    not a true family
  6. 2582518Protein automated matches [232407] (3 species)
    not a true protein
  7. 2582519Species Human (Homo sapiens) [TaxId:9606] [232408] (17 PDB entries)
  8. 2582545Domain d6b3si2: 6b3s I:481-502 [342232]
    Other proteins in same PDB: d6b3sa1, d6b3sa2, d6b3sb1, d6b3sb3, d6b3sd1, d6b3sd2, d6b3se1, d6b3se3, d6b3sg1, d6b3sg2, d6b3si1, d6b3si3, d6b3sk1, d6b3sk2, d6b3sl1, d6b3sl2
    automated match to d1yy9a4
    complexed with bma, man, nag

Details for d6b3si2

PDB Entry: 6b3s (more details), 2.8 Å

PDB Description: crystal structure of the fab fragment of necitumumab (fab11f8) in complex with domain iii from a cetuximab resistant variant of egfr (segfrd3-s468r)
PDB Compounds: (I:) Epidermal growth factor receptor

SCOPe Domain Sequences for d6b3si2:

Sequence; same for both SEQRES and ATOM records: (download)

>d6b3si2 g.3.9.0 (I:481-502) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vchalcspegcwgpeprdcvsc

SCOPe Domain Coordinates for d6b3si2:

Click to download the PDB-style file with coordinates for d6b3si2.
(The format of our PDB-style files is described here.)

Timeline for d6b3si2: