SCOPe 2.08: Domain d6b8ub_: 6b8u B:

Lineage for d6b8ub_ (6b8u B:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)

8. Domain d6b8ub_: 6b8u B: [341769]
   automated match to d4e26a_
   complexed with 8en

Details for d6b8ub_

PDB Entry: 6b8u, 2.68 Å

PDB Description: crystals structure of b-raf kinase domain in complex with an imidazopyridinyl benzamide inhibitor

PDB Compounds: (B:) Serine/threonine-protein kinase B-raf

SCOPe Domain Sequences for d6b8ub_:

Sequence, based on SEQRES records:

>d6b8ub_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sddweipdgqitvgqrigsgsfgtvykgkwhgdvavkmlnvtaptpqqlqafknevgvlr
ktrhvnillfmgystkpqlaivtqwcegsslyhhlhiietkfemiklidiarqtaqgmdy
lhaksiihrdlksnniflhedltvkigdfglatvksrwsgshqfeqlsgsilwmapevir
mqdknpysfqsdvyafgivlyelmtgqlpysninnrdqiifmvgrgylspdlskvrsncp
kamkrlmaeclkkkrderplfpqilasiellars

Sequence, based on observed residues (ATOM records):

>d6b8ub_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sddweipdgqitvgqrigsgsfgtvykgkwhgdvavkmaptpqqlqafknevgvlrktrh
vnillfmgystkpqlaivtqwcegsslyhhlhiietkfemiklidiarqtaqgmdylhak
siihrdlksnniflhedltvkigdfgsilwmapevirmnpysfqsdvyafgivlyelmtg
qlpysninnrdqiifmvgrgylspdlskvrsncpkamkrlmaeclkkkrderplfpqila
siellars

Timeline for d6b8ub_:

• d6b8ub_ first appeared in SCOPe 2.06
  
• d6b8ub_ appears in SCOPe 2.07