SCOPe 2.08: Domain d5op6a_: 5op6 A:

Lineage for d5op6a_ (5op6 A:)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.82: Double-stranded beta-helix [51181] (7 superfamilies)
   one turn of helix is made by two pairs of antiparallel strands linked with short turns
   has appearance of a sandwich of distinct architecture and jelly-roll topology

4. Superfamily b.82.2: Clavaminate synthase-like [51197] (16 families)
   Iron and ketoglutarate-dependent enzymes; elaborated version of this common fold

5. Family b.82.2.6: Hypoxia-inducible factor HIF ihhibitor (FIH1) [82194] (1 protein)

6. Protein Hypoxia-inducible factor HIF ihhibitor (FIH1) [82195] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [82196] (38 PDB entries)

8. Domain d5op6a_: 5op6 A: [340273]
   automated match to d3p3na_
   protein/DNA complex; complexed with a0w, gol, so4, zn

Details for d5op6a_

PDB Entry: 5op6, 2.45 Å

PDB Description: factor inhibiting hif (fih) in complex with zinc and gsk128863

PDB Compounds: (A:) Hypoxia-inducible factor 1-alpha inhibitor

SCOPe Domain Sequences for d5op6a_:

Sequence, based on SEQRES records:

>d5op6a_ b.82.2.6 (A:) Hypoxia-inducible factor HIF ihhibitor (FIH1) {Human (Homo sapiens) [TaxId: 9606]}
epreeagalgpawdesqlrsysfptrpiprlsqsdpraeelieneepvvltdtnlvypal
kwdleylqenigngdfsvysasthkflyydekkmanfqnfkprsnreemkfhefveklqd
iqqrggeerlylqqtlndtvgrkivmdflgfnwnwinkqqgkrgwgqltsnllligmegn
vtpahydeqqnffaqikgykrcilfppdqfeclypypvhhpcdrqsqvdfdnpdyerfpn
fqnvvgyetvvgpgdvlyipmywwhhiesllnggititvnfwykgaptpkrieyplkahq
kvaimrniekmlgealgnpqevgpllntmikgryn

Sequence, based on observed residues (ATOM records):

>d5op6a_ b.82.2.6 (A:) Hypoxia-inducible factor HIF ihhibitor (FIH1) {Human (Homo sapiens) [TaxId: 9606]}
epreeagalgpawdesqlrsysfptrpiprlsqsdpraeelieneepvvltdtnlvypal
kwdleylqenigngdfsvysasthkflyydekkmanfqnfkpnreemkfhefveklqdiq
qrggeerlylqqtlndtvgrkivmdflgfnwnwinkqqgkrgwgqltsnllligmegnvt
pahydeqqnffaqikgykrcilfppdqfeclypypvhhpcdrqsqvdfdnpdyerfpnfq
nvvgyetvvgpgdvlyipmywwhhiesllnggititvnfwykgaptpkrieyplkahqkv
aimrniekmlgealgnpqevgpllntmikgryn

Timeline for d5op6a_:

• d5op6a_ first appeared in SCOPe 2.06
  
• d5op6a_ appears in SCOPe 2.07