SCOPe 2.08: Domain d5wala2: 5wal A:1177-1177

Lineage for d5wala2 (5wal A:1177-1177)

1. Root: SCOPe 2.08

2. Class l: Artifacts [310555] (1 fold)

3. Fold l.1: Tags [310573] (1 superfamily)

4. Superfamily l.1.1: Tags [310607] (1 family)

5. Family l.1.1.1: Tags [310682] (2 proteins)

6. Protein C-terminal Tags [310895] (1 species)

7. Species Synthetic [311502] (6039 PDB entries)

8. Domain d5wala2: 5wal A:1177-1177 [338825]
   Other proteins in same PDB: d5wala1
   complexed with 9zs

Details for d5wala2

PDB Entry: 5wal, 2.45 Å

PDB Description: identification of an imidazopyridine scaffold to generate potent and selective tyk2 inhibitors that demonstrate activity in an in vivo psoriasis model

PDB Compounds: (A:) Non-receptor tyrosine-protein kinase TYK2

SCOPe Domain Sequences for d5wala2:

Sequence; same for both SEQRES and ATOM records:

>d5wala2 l.1.1.1 (A:1177-1177) C-terminal Tags {Synthetic}
r

Timeline for d5wala2:

• d5wala2 first appeared in SCOPe 2.06
  
• d5wala2 appears in SCOPe 2.07