SCOPe 2.08: Domain d5w8va1: 5w8v A:4-216

Lineage for d5w8va1 (5w8v A:4-216)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.61: PRTase-like [53270] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 6 strands, order 321456; strand 3 is antiparallel to the rest

4. Superfamily c.61.1: PRTase-like [53271] (3 families)

5. Family c.61.1.1: Phosphoribosyltransferases (PRTases) [53272] (16 proteins)

6. Protein Hypoxanthine-guanine PRTase (HGPRTase) [53283] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [53284] (20 PDB entries)

8. Domain d5w8va1: 5w8v A:4-216 [338770]
   Other proteins in same PDB: d5w8va2
   automated match to d4rade_
   complexed with 9yp, mg

Details for d5w8va1

PDB Entry: 5w8v, 2.35 Å

PDB Description: human hgprt in complex with [(2-[(guanin-9-yl)methyl]propane-1,3- diyl)bis(oxy)]bis(methylene)diphosphonic acid

PDB Compounds: (A:) hypoxanthine-guanine phosphoribosyltransferase

SCOPe Domain Sequences for d5w8va1:

Sequence, based on SEQRES records:

>d5w8va1 c.61.1.1 (A:4-216) Hypoxanthine-guanine PRTase (HGPRTase) {Human (Homo sapiens) [TaxId: 9606]}
spgvvisddepgydldlfcipnhyaedlervfiphglimdrterlardvmkemgghhiva
lcvlkggykffadlldyikalnrnsdrsipmtvdfirlksycndqstgdikviggddlst
ltgknvlivediidtgktmqtllslvrqynpkmvkvasllvkrtprsvgykpdfvgfeip
dkfvvgyaldyneyfrdlnhvcvisetgkakyk

Sequence, based on observed residues (ATOM records):

>d5w8va1 c.61.1.1 (A:4-216) Hypoxanthine-guanine PRTase (HGPRTase) {Human (Homo sapiens) [TaxId: 9606]}
spgvvisddepgydldlfcipnhyaedlervfiphglimdrterlardvmkemgghhiva
lcvlkggykffadlldyikalnrnsdrsipmtvdfirlksyikviggddlstltgknvli
vediidtgktmqtllslvrqynpkmvkvasllvkrtprsvgykpdfvgfeipdkfvvgya
ldyneyfrdlnhvcvisetgkakyk

Timeline for d5w8va1:

• d5w8va1 first appeared in SCOPe 2.06
  
• d5w8va1 appears in SCOPe 2.07