Lineage for d5gtyb_ (5gty B:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2542179Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2542180Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2542316Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2543502Protein EGF receptor tyrosine kinase, Erbb-1 [82795] (1 species)
    PTK group; EGFR subfamily; membrane spanning protein tyrosine kinase
  7. 2543503Species Human (Homo sapiens) [TaxId:9606] [82796] (103 PDB entries)
    Uniprot P00533 702-1018
  8. 2543611Domain d5gtyb_: 5gty B: [338508]
    automated match to d3ikaa_
    complexed with 816, edo

Details for d5gtyb_

PDB Entry: 5gty (more details), 3.14 Å

PDB Description: crystal structure of egfr 696-1022 t790m in complex with lxx-6-26
PDB Compounds: (B:) Epidermal growth factor receptor

SCOPe Domain Sequences for d5gtyb_:

Sequence, based on SEQRES records: (download)

>d5gtyb_ d.144.1.7 (B:) EGF receptor tyrosine kinase, Erbb-1 {Human (Homo sapiens) [TaxId: 9606]}
nqallrilketefkkikvlgsgafgtvykglwipegekvkipvaikelreatspkankei
ldeayvmasvdnphvcrllgicltstvqlimqlmpfgclldyvrehkdnigsqyllnwcv
qiakgmnyledrrlvhrdlaarnvlvktpqhvkitdfglakllgaeekeyhaeggkvpik
wmalesilhriythqsdvwsygvtvwelmtfgskpydgipaseissilekgerlpqppic
tidvymimvkcwmidadsrpkfreliiefskmardpqrylviqgdermhlpsptdsnfyr
almdeedmddvvdad

Sequence, based on observed residues (ATOM records): (download)

>d5gtyb_ d.144.1.7 (B:) EGF receptor tyrosine kinase, Erbb-1 {Human (Homo sapiens) [TaxId: 9606]}
nqallrilketefkkikvlgsgafgtvykglwipegekvkipvaikelrekankeildea
yvmasvdnphvcrllgicltstvqlimqlmpfgclldyvrehkdnigsqyllnwcvqiak
gmnyledrrlvhrdlaarnvlvktpqhvkitdfglakllkvpikwmalesilhriythqs
dvwsygvtvwelmtfgskpydgipaseissilekgerlpqppictidvymimvkcwmida
dsrpkfreliiefskmardpqrylviqgdermhlpsptdsnfyralmdeedmddvvdad

SCOPe Domain Coordinates for d5gtyb_:

Click to download the PDB-style file with coordinates for d5gtyb_.
(The format of our PDB-style files is described here.)

Timeline for d5gtyb_: