Lineage for d5obra_ (5obr A:)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2218047Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2218048Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2218179Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2218253Protein Aurora-related kinase 1 (aurora-2) [90038] (1 species)
    OPK group; AIRK subfamily; serine/threonine kinase
  7. 2218254Species Human (Homo sapiens) [TaxId:9606] [90039] (62 PDB entries)
  8. 2218322Domain d5obra_: 5obr A: [337563]
    automated match to d3h10a_
    complexed with 9qt, mg, ske

Details for d5obra_

PDB Entry: 5obr (more details), 2.62 Å

PDB Description: aurora a kinase in complex with 2-(3-chloro-5-fluorophenyl)quinoline- 4-carboxylic acid and jnj-7706621
PDB Compounds: (A:) Aurora kinase A

SCOPe Domain Sequences for d5obra_:

Sequence, based on SEQRES records: (download)

>d5obra_ d.144.1.7 (A:) Aurora-related kinase 1 (aurora-2) {Human (Homo sapiens) [TaxId: 9606]}
rqwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreveiq
shlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelanals
ychskrvihrdikpenlllgsagelkiadfgwsvhapssrrttlcgtldylppemiegrm
hdekvdlwslgvlcyeflvgkppfeantyqetykrisrveftfpdfvtegardlisrllk
hnpsqrpmlrevlehpwitansskp

Sequence, based on observed residues (ATOM records): (download)

>d5obra_ d.144.1.7 (A:) Aurora-related kinase 1 (aurora-2) {Human (Homo sapiens) [TaxId: 9606]}
rqwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreveiq
shlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelanals
ychskrvihrdikpenlllgsagelkiadfgwsvhgtldylppemiegrmhdekvdlwsl
gvlcyeflvgkppfeantyqetykrisrveftfpdfvtegardlisrllkhnpsqrpmlr
evlehpwitansskp

SCOPe Domain Coordinates for d5obra_:

Click to download the PDB-style file with coordinates for d5obra_.
(The format of our PDB-style files is described here.)

Timeline for d5obra_: