SCOPe 2.07: Domain d5kyba_: 5kyb A:

Lineage for d5kyba_ (5kyb A:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (24 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.9: Ubiquitin carboxyl-terminal hydrolase, UCH [82568] (6 proteins)
   Pfam PF00443

6. Protein Ubiquitin carboxyl-terminal hydrolase 7 (USP7, HAUSP) [82569] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [82570] (25 PDB entries)

8. Domain d5kyba_: 5kyb A: [337523]
   automated match to d1nbfa_
   complexed with gol; mutant

Details for d5kyba_

PDB Entry: 5kyb, 2.2 Å

PDB Description: crystal structure of the apo-form of usp7 catalytic domain [v302k] mutant

PDB Compounds: (A:) Ubiquitin carboxyl-terminal hydrolase 7

SCOPe Domain Sequences for d5kyba_:

Sequence, based on SEQRES records:

>d5kyba_ d.3.1.9 (A:) Ubiquitin carboxyl-terminal hydrolase 7 (USP7, HAUSP) {Human (Homo sapiens) [TaxId: 9606]}
tgyvglknqgatcymnsllqtlfftnqlrkavymmptegddssksvplalqrvfyelqhs
dkpvgtkkltksfgwetldsfmqhdvqelcrklldnvenkmkgtcvegtipklfrgkmvs
yiqckevdyrsdrredyydiqlsikgkknifesfvdyvaveqldgdnkydagehglqeae
kgvkfltlppvlhlqlmrfmydpqtdqnikindrfefpeqlpldeflqktdpkdpanyil
havlvhsgdnhgghyvvylnpkgdgkwckfdddvvsrctkeeaiehnygghdddlsvrhc
tnaymlvyiresklsevlqavtdhdipqqlverlqeekrieaq

Sequence, based on observed residues (ATOM records):

>d5kyba_ d.3.1.9 (A:) Ubiquitin carboxyl-terminal hydrolase 7 (USP7, HAUSP) {Human (Homo sapiens) [TaxId: 9606]}
tgyvglknqgatcymnsllqtlfftnqlrkavymmptegddssksvplalqrvfyelqhs
dkpvgtkkltksfgwetldsfmqhdvqelcrklldnvenkmkgtcvegtipklfrgkmvs
yiqckevdyrsdrredyydiqlsikgkknifesfvdyvaveqldgdnkydagehglqeae
kgvkfltlppvlhlqlmrfmynikindrfefpeqlpldeflqktdpkdpanyilhavlvh
sgdnhgghyvvylnpkgdgkwckfdddvvsrctkeeaiehnygghhctnaymlvyiresk
lsevlqavtdhdipqqlverlqeekrieaq

Timeline for d5kyba_:

• d5kyba_ first appeared in SCOPe 2.06
  
• d5kyba_ appears in the current release, SCOPe 2.08