SCOPe 2.07: Domain d5gxoa1: 5gxo A:25-107

Lineage for d5gxoa1 (5gxo A:25-107)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.2: Long alpha-hairpin [46556] (20 superfamilies)
   2 helices; antiparallel hairpin, left-handed twist

4. Superfamily a.2.11: Fe,Mn superoxide dismutase (SOD), N-terminal domain [46609] (2 families)
   automatically mapped to Pfam PF00081

5. Family a.2.11.1: Fe,Mn superoxide dismutase (SOD), N-terminal domain [46610] (4 proteins)

6. Protein Mn superoxide dismutase (MnSOD) [46618] (9 species)

7. Species Human (Homo sapiens) [TaxId:9606] [46619] (35 PDB entries)

8. Domain d5gxoa1: 5gxo A:25-107 [337475]
   Other proteins in same PDB: d5gxoa2, d5gxob2
   automated match to d1luva1
   complexed with mn

Details for d5gxoa1

PDB Entry: 5gxo, 2.3 Å

PDB Description: discovery of a compound that activates sirt3 to deacetylate manganese superoxide dismutase

PDB Compounds: (A:) Superoxide dismutase [Mn], mitochondrial

SCOPe Domain Sequences for d5gxoa1:

Sequence; same for both SEQRES and ATOM records:

>d5gxoa1 a.2.11.1 (A:25-107) Mn superoxide dismutase (MnSOD) {Human (Homo sapiens) [TaxId: 9606]}
khslpdlpydygalephinaqimqlhhskhhaayvnnlnvteekyqealakgdvtaqial
qpalkfnggghinhsifwtnlsp

Timeline for d5gxoa1:

• d5gxoa1 first appeared in SCOPe 2.06
  
• d5gxoa1 appears in the current release, SCOPe 2.08