SCOPe 2.04: Domain d1qs4a_: 1qs4 A:

Lineage for d1qs4a_ (1qs4 A:)

1. Root: SCOPe 2.04

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest

4. Superfamily c.55.3: Ribonuclease H-like [53098] (15 families)
   consists of one domain of this fold

5. Family c.55.3.2: Retroviral integrase, catalytic domain [53107] (2 proteins)

6. Protein Retroviral integrase, catalytic domain [53108] (3 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [53110] (42 PDB entries)

8. Domain d1qs4a_: 1qs4 A: [33658]
   protein/DNA complex; complexed with 100, mg

Details for d1qs4a_

PDB Entry: 1qs4, 2.1 Å

PDB Description: core domain of hiv-1 integrase complexed with mg++ and 1-(5- chloroindol-3-yl)-3-hydroxy-3-(2h-tetrazol-5-yl)-propenone

PDB Compounds: (A:) protein (hiv-1 integrase (e.c.2.7.7.49))

SCOPe Domain Sequences for d1qs4a_:

Sequence, based on SEQRES records:

>d1qs4a_ c.55.3.2 (A:) Retroviral integrase, catalytic domain {Human immunodeficiency virus type 1 [TaxId: 11676]}
cspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvht
dngsnftsttvkaacewggikqefgipynpqsqgviesmnkelkkiigqvrdqaehlkta
vqmavfihnkkrkggiggysagerivdiiatdiq

Sequence, based on observed residues (ATOM records):

>d1qs4a_ c.55.3.2 (A:) Retroviral integrase, catalytic domain {Human immunodeficiency virus type 1 [TaxId: 11676]}
cspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvht
dngsnftsttvkaacewggikqefgpqsqgviesmnkelkkiigqvrdqaehlktavqma
vfihnkkrkggiggysagerivdiiatdiq

Timeline for d1qs4a_:

• d1qs4a_ first appeared (with stable ids) in SCOP 1.55
  
• d1qs4a_ appears in SCOPe 2.03
  
• d1qs4a_ appears in SCOPe 2.05
  
• d1qs4a_ appears in the current release, SCOPe 2.08