SCOPe 2.08: Domain d5o7ac2: 5o7a C:246-440

Lineage for d5o7ac2 (5o7a C:246-440)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.79: Bacillus chorismate mutase-like [55297] (9 superfamilies)
   core: beta-alpha-beta-alpha-beta(2); mixed beta-sheet: order: 1423, strand 4 is antiparallel to the rest

4. Superfamily d.79.2: Tubulin C-terminal domain-like [55307] (2 families)

5. Family d.79.2.1: Tubulin, C-terminal domain [55308] (4 proteins)

6. Protein automated matches [227071] (7 species)
   not a true protein

7. Species Cow (Bos taurus) [TaxId:9913] [226565] (136 PDB entries)

8. Domain d5o7ac2: 5o7a C:246-440 [336536]
   Other proteins in same PDB: d5o7aa1, d5o7ab1, d5o7ac1, d5o7ad1, d5o7ae_, d5o7af1, d5o7af2
   automated match to d4i50a2
   complexed with 9n5, acp, gdp, gtp, mg

Details for d5o7ac2

PDB Entry: 5o7a, 2.5 Å

PDB Description: quinolin-6-yloxyacetamides are microtubule destabilizing agents that bind to the colchicine site of tubulin

PDB Compounds: (C:) Tubulin alpha-1B chain

SCOPe Domain Sequences for d5o7ac2:

Sequence; same for both SEQRES and ATOM records:

>d5o7ac2 d.79.2.1 (C:246-440) automated matches {Cow (Bos taurus) [TaxId: 9913]}
galnvdltefqtnlvpyprihfplatyapvisaekayheqlsvaeitnacfepanqmvkc
dprhgkymaccllyrgdvvpkdvnaaiatiktkrsiqfvdwcptgfkvginyqpptvvpg
gdlakvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefsearedm
aalekdyeevgvdsv

Timeline for d5o7ac2:

• d5o7ac2 first appeared in SCOPe 2.06
  
• d5o7ac2 appears in SCOPe 2.07