Lineage for d5x5qa_ (5x5q A:)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2972108Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
    contains large mixed beta-sheet
  4. 2972109Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families) (S)
    automatically mapped to Pfam PF00303
  5. 2972110Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (4 proteins)
  6. 2972208Protein Thymidylate synthase [55833] (7 species)
  7. 2972355Species Human (Homo sapiens) [TaxId:9606] [55840] (47 PDB entries)
  8. 2972467Domain d5x5qa_: 5x5q A: [336400]
    automated match to d2aaza_
    complexed with d16, ump

Details for d5x5qa_

PDB Entry: 5x5q (more details), 2.79 Å

PDB Description: human thymidylate synthase complexed with dump and raltitrexed
PDB Compounds: (A:) Thymidylate synthase

SCOPe Domain Sequences for d5x5qa_:

Sequence; same for both SEQRES and ATOM records: (download)

>d5x5qa_ d.117.1.1 (A:) Thymidylate synthase {Human (Homo sapiens) [TaxId: 9606]}
pphgelqylgqiqhilrcgvrkddrtgtgtlsvfgmqaryslrdefpllttkrvfwkgvl
eellwfikgstnakelsskgvkiwdangsrdfldslgfstreegdlgpvygfqwrhfgae
yrdmesdysgqgvdqlqrvidtiktnpddrriimcawnprdlplmalppchalcqfyvvn
selscqlyqrsgdmglgvpfniasyalltymiahitglkpgdfihtlgdahiylnhiepl
kiqlqreprpfpklrilrkvekiddfkaedfqiegynphptikmem

SCOPe Domain Coordinates for d5x5qa_:

Click to download the PDB-style file with coordinates for d5x5qa_.
(The format of our PDB-style files is described here.)

Timeline for d5x5qa_: