SCOPe 2.08: Domain d5o2bb_: 5o2b B:

Lineage for d5o2bb_ (5o2b B:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)

8. Domain d5o2bb_: 5o2b B: [336343]
   Other proteins in same PDB: d5o2ba2
   automated match to d4pwna_
   complexed with ks1, na

Details for d5o2bb_

PDB Entry: 5o2b, 2.04 Å

PDB Description: crystal structure of wnk3 kinase domain in a diphosphorylated state and in a complex with the inhibitor pp-121

PDB Compounds: (B:) Serine/threonine-protein kinase WNK3

SCOPe Domain Sequences for d5o2bb_:

Sequence, based on SEQRES records:

>d5o2bb_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mkavatspsgrflkfdielgrgafktvykgldtetwvevawcelqdrkltkaeqqrfkee
aemlkglqhpnivrfydswesilkgkkcivlvtelmtsgtlktylkrfkvmkpkvlrswc
rqilkglqflhtrtppiihrdlkcdnifitgptgsvkigdlglatlmrtsfaksvigtpe
fmapemyeehydesvdvyafgmcmlematseypysecqnaaqiyrkvtsgikpasfnkvt
dpevkeiiegcirqnkserlsirdllnhaffa

Sequence, based on observed residues (ATOM records):

>d5o2bb_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mkavatspsgrflkfdielgrgafktvykgldtetwvevawcelqdtkaeqqrfkeeaem
lkglqhpnivrfydswesilkgkkcivlvtelmtsgtlktylkrfkvmkpkvlrswcrqi
lkglqflhtrtppiihrdlkcdnifitgptgsvkigdlglatlmtpefmapemyeehyde
svdvyafgmcmlematseypysecqnaaqiyrkvtskpasfnkvtdpevkeiiegcirqn
kserlsirdllnhaffa

Timeline for d5o2bb_:

• d5o2bb_ first appeared in SCOPe 2.06
  
• d5o2bb_ appears in SCOPe 2.07