SCOPe 2.08: Domain d5valb_: 5val B:

Lineage for d5valb_ (5val B:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)

8. Domain d5valb_: 5val B: [336263]
   automated match to d4e26a_
   complexed with 92d

Details for d5valb_

PDB Entry: 5val, 2.26 Å

PDB Description: braf in complex with n-(3-(tert-butyl)phenyl)-4-methyl-3-(6- morpholinopyrimidin-4-yl)benzamide

PDB Compounds: (B:) Serine/threonine-protein kinase B-raf

SCOPe Domain Sequences for d5valb_:

Sequence, based on SEQRES records:

>d5valb_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ddweipdgqitvgqrigsgsfgtvykgkwhgdvavkmlnvtaptpqqlqafknevgvlrk
trhvnillfmgystkpqlaivtqwcegsslyhhlhiietkfemiklidiarqtaqgmdyl
haksiihrdlksnniflhedltvkigdfglatvksrwsgshqfeqlsgsilwmapevirm
qdknpysfqsdvyafgivlyelmtgqlpysninnrdqiifmvgrgylspdlskvrsncpk
amkrlmaeclkkkrderplfpqilasiellarsl

Sequence, based on observed residues (ATOM records):

>d5valb_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ddweipdgqitvgqrigsgsfgtvykgkwhgdvavkmlnvtaptpqqlqafknevgvlrk
trhvnillfmgystkpqlaivtqwcegsslyhhlhiietkfemiklidiarqtaqgmdyl
haksiihrdlksnniflhedltvkigdfglgsilwmapevirmnpysfqsdvyafgivly
elmtgqlpysninnrdqiifmvgrgylspdlskvrsncpkamkrlmaeclkkkrderplf
pqilasiellarsl

Timeline for d5valb_:

• d5valb_ first appeared in SCOPe 2.06
  
• d5valb_ appears in SCOPe 2.07