SCOPe 2.06: Domain d5gsqb1: 5gsq B:237-339

Lineage for d5gsqb1 (5gsq B:237-339)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein Immunoglobulin heavy chain gamma constant domain 2, CH2-gamma [88584] (4 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88585] (57 PDB entries)
   Uniprot P01857 #118-327 ! Uniprot P01857 118-327 # GC1_HUMAN Ig gamma-1 chain C region

8. Domain d5gsqb1: 5gsq B:237-339 [336006]
   Other proteins in same PDB: d5gsqa2, d5gsqb2, d5gsqc2, d5gsqd2
   automated match to d1hzhk3
   complexed with bma, gal, man, nag, sia

Details for d5gsqb1

PDB Entry: 5gsq, 1.85 Å

PDB Description: crystal structure of igg fc with a homogeneous glycoform and antibody- dependent cellular cytotoxicity

PDB Compounds: (B:) Ig gamma-1 chain C region

SCOPe Domain Sequences for d5gsqb1:

Sequence; same for both SEQRES and ATOM records:

>d5gsqb1 b.1.1.2 (B:237-339) Immunoglobulin heavy chain gamma constant domain 2, CH2-gamma {Human (Homo sapiens) [TaxId: 9606]}
gpsvflfppkpkdtlmisrtpevtcvvvdvshedpevkfnwyvdgvevhnaktkpreeqy
nstyrvvsvltvlhqdwlngkeykckvsnkalpapiektiska

Timeline for d5gsqb1:

• d5gsqb1 is new in SCOPe 2.06-stable
  
• d5gsqb1 appears in SCOPe 2.07
  
• d5gsqb1 appears in the current release, SCOPe 2.08