Lineage for d5kaea3 (5kae A:526-725)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 2009599Fold a.118: alpha-alpha superhelix [48370] (25 superfamilies)
    multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix
  4. 2009600Superfamily a.118.1: ARM repeat [48371] (26 families) (S)
  5. 2009807Family a.118.1.6: Phoshoinositide 3-kinase (PI3K) helical domain [48399] (1 protein)
    automatically mapped to Pfam PF00613
  6. 2009808Protein Phoshoinositide 3-kinase (PI3K) helical domain [48400] (2 species)
  7. 2009809Species Human (Homo sapiens) [TaxId:9606] [48402] (65 PDB entries)
  8. 2009864Domain d5kaea3: 5kae A:526-725 [335597]
    Other proteins in same PDB: d5kaea1, d5kaea2, d5kaea4
    automated match to d1e8ya1
    complexed with 6rf, so4

Details for d5kaea3

PDB Entry: 5kae (more details), 2.65 Å

PDB Description: crystal structure of human pi3k-gamma in complex with quinoline- containing inhibitor 5g
PDB Compounds: (A:) Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

SCOPe Domain Sequences for d5kaea3:

Sequence, based on SEQRES records: (download)

>d5kaea3 a.118.1.6 (A:526-725) Phoshoinositide 3-kinase (PI3K) helical domain {Human (Homo sapiens) [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d5kaea3 a.118.1.6 (A:526-725) Phoshoinositide 3-kinase (PI3K) helical domain {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d5kaea3:

Click to download the PDB-style file with coordinates for d5kaea3.
(The format of our PDB-style files is described here.)

Timeline for d5kaea3: