SCOPe 2.07: Domain d5m6xa_: 5m6x A:

Lineage for d5m6xa_ (5m6x A:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.116: GTPase activation domain, GAP [48349] (1 superfamily)
   multihelical

4. Superfamily a.116.1: GTPase activation domain, GAP [48350] (3 families)

5. Family a.116.1.1: BCR-homology GTPase activation domain (BH-domain) [48351] (6 protein domains)
   Pfam PF00620

6. Protein automated matches [334155] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [334156] (2 PDB entries)

8. Domain d5m6xa_: 5m6x A: [334195]
   Other proteins in same PDB: d5m6xb_, d5m6xi_
   automated match to d1grnb_
   complexed with gdp, mg, mgf

Details for d5m6xa_

PDB Entry: 5m6x, 2.4 Å

PDB Description: crystal structure of human rhogap mutated in its arginine finger (r85a) in complex with rhoa.gdp.mgf3- human

PDB Compounds: (A:) Rho GTPase-activating protein 1

SCOPe Domain Sequences for d5m6xa_:

Sequence, based on SEQRES records:

>d5m6xa_ a.116.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qqfgvslqhlqeknpeqepipivlretvaylqahalttegifarsantqvvrevqqkynm
glpvdfdqynelhlpavilktflrelpeplltfdlyphvvgflnidesqrvpatlqvlqt
lpeenyqvlrfltaflvqisahsdqnkmtntnlavvfgpnllwakdaaitlkainpintf
tkflldhqgelf

Sequence, based on observed residues (ATOM records):

>d5m6xa_ a.116.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qqfgvslqhlqeknpipivlretvaylqahalttegifarsantqvvrevqqkynmglpv
dfdqynelhlpavilktflrelpeplltfdlyphvvgflnidesqrvpatlqvlqtlpee
nyqvlrfltaflvqisahsdqnkmtntnlavvfgpnllwakdaaitlkainpintftkfl
ldhqgelf

Timeline for d5m6xa_:

• d5m6xa_ first appeared in SCOPe 2.06