SCOPe 2.08: Domain d5m70f_: 5m70 F:

Lineage for d5m70f_ (5m70 F:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.116: GTPase activation domain, GAP [48349] (1 superfamily)
   multihelical

4. Superfamily a.116.1: GTPase activation domain, GAP [48350] (3 families)

5. Family a.116.1.1: BCR-homology GTPase activation domain (BH-domain) [48351] (6 proteins)
   Pfam PF00620

6. Protein automated matches [334155] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [334156] (3 PDB entries)

8. Domain d5m70f_: 5m70 F: [334157]
   Other proteins in same PDB: d5m70b_, d5m70g_
   automated match to d1grnb_
   complexed with alf, gdp, mg

Details for d5m70f_

PDB Entry: 5m70, 2.2 Å

PDB Description: crystal structure of human rhogap mutated in its arginin finger (r85a) in complex with rhoa.gdp.alf4- human

PDB Compounds: (F:) Rho GTPase-activating protein 1

SCOPe Domain Sequences for d5m70f_:

Sequence, based on SEQRES records:

>d5m70f_ a.116.1.1 (F:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qqfgvslqhlqeknpeqepipivlretvaylqahalttegifarsantqvvrevqqkynm
glpvdfdqynelhlpavilktflrelpeplltfdlyphvvgflnidesqrvpatlqvlqt
lpeenyqvlrfltaflvqisahsdqnkmtntnlavvfgpnllwakdaaitlkainpintf
tkflldhqgelf

Sequence, based on observed residues (ATOM records):

>d5m70f_ a.116.1.1 (F:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qqfgvslqhlqeknpipivlretvaylqahalttegifarsantqvvrevqqkynmglpv
dfdqynelhlpavilktflrelpeplltfdlyphvvgflnidesqrvpatlqvlqtlpee
nyqvlrfltaflvqisahsdqnkmtntnlavvfgpnllwakdaaitlkainpintftkfl
ldhqgelf

Timeline for d5m70f_:

• d5m70f_ first appeared in SCOPe 2.06
  
• d5m70f_ appears in SCOPe 2.07