SCOPe 2.08: Domain d5uo8b_: 5uo8 B:

Lineage for d5uo8b_ (5uo8 B:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.174: Nitric oxide (NO) synthase oxygenase domain [56511] (1 superfamily)
   unusual fold

4. Superfamily d.174.1: Nitric oxide (NO) synthase oxygenase domain [56512] (1 family)
   automatically mapped to Pfam PF02898

5. Family d.174.1.1: Nitric oxide (NO) synthase oxygenase domain [56513] (2 proteins)

6. Protein Nitric oxide (NO) synthase oxygenase domain [56514] (6 species)

7. Species Human (Homo sapiens) [TaxId:9606] [56516] (33 PDB entries)

8. Domain d5uo8b_: 5uo8 B: [333920]
   automated match to d3e7sa_
   complexed with 8ev, btb, gd, gol, h4b, hem, zn

Details for d5uo8b_

PDB Entry: 5uo8, 2.18 Å

PDB Description: structure of human endothelial nitric oxide synthase heme domain in complex with 3-[(2-aminoquinolin-7-yl)methoxy]-5-((methylamino) methyl)benzonitrile

PDB Compounds: (B:) Nitric oxide synthase, endothelial

SCOPe Domain Sequences for d5uo8b_:

Sequence, based on SEQRES records:

>d5uo8b_ d.174.1.1 (B:) Nitric oxide (NO) synthase oxygenase domain {Human (Homo sapiens) [TaxId: 9606]}
kfprvknwevgsitydtlsaqaqqdgpctprrclgslvfprklqgrpspgppapeqllsq
ardfinqyyssikrsgsqaheqrlqeveaevaatgtyqlreselvfgakqawrnaprcvg
riqwgklqvfdardcrsaqemftyicnhikyatnrgnlrsaitvfpqrcpgrgdfriwns
qlvryagyrqqdgsvrgdpanveitelciqhgwtpgngrfdvlplllqapdeppelfllp
pelvlevplehptlewfaalglrwyalpavsnmlleigglefpaapfsgwymsteigtrn
lcdphryniledvavcmdldtrttsslwkdkaaveinvavlhsyqlakvtivdhhaatas
fmkhleneqkarggcpadwawivppisgsltpvfhqemvnyflspafryqpdpw

Sequence, based on observed residues (ATOM records):

>d5uo8b_ d.174.1.1 (B:) Nitric oxide (NO) synthase oxygenase domain {Human (Homo sapiens) [TaxId: 9606]}
kfprvknwevgsitydtlsaqaqqdgpctprrclgslvfpapeqllsqardfinqyyssi
krsgsqaheqrlqeveaevaatgtyqlreselvfgakqawrnaprcvgriqwgklqvfda
rdcrsaqemftyicnhikyatnrgnlrsaitvfpqrcpgrgdfriwnsqlvryagyrqqd
gsvrgdpanveitelciqhgwtpgngrfdvlplllqapdeppelfllppelvlevplehp
tlewfaalglrwyalpavsnmlleigglefpaapfsgwymsteigtrnlcdphryniled
vavcmdldtrttsslwkdkaaveinvavlhsyqlakvtivdhhaatasfmkhleneqkar
ggcpadwawivppisgsltpvfhqemvnyflspafryqpdpw

Timeline for d5uo8b_:

• d5uo8b_ first appeared in SCOPe 2.06
  
• d5uo8b_ appears in SCOPe 2.07