SCOPe 2.08: Domain d5nood_: 5noo D:

Lineage for d5nood_ (5noo D:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
   contains large mixed beta-sheet

4. Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families)
   automatically mapped to Pfam PF00303

5. Family d.117.1.0: automated matches [227244] (1 protein)
   not a true family

6. Protein automated matches [227010] (5 species)
   not a true protein

7. Species Nematode (Caenorhabditis elegans) [TaxId:6239] [236135] (6 PDB entries)

8. Domain d5nood_: 5noo D: [333873]
   automated match to d4irra_
   complexed with d16, ump

Details for d5nood_

PDB Entry: 5noo, 2.9 Å

PDB Description: crystal structure of c.elegans thymidylate synthase in complex with dump and tomudex

PDB Compounds: (D:) Thymidylate synthase

SCOPe Domain Sequences for d5nood_:

Sequence, based on SEQRES records:

>d5nood_ d.117.1.0 (D:) automated matches {Nematode (Caenorhabditis elegans) [TaxId: 6239]}
hlnqdeykylkqveqilregtrrddrtgtgtisifgmqskyclrngtipllttkrvywkg
vleellwfisgstdgkllmeknvkiwekngdrafldnlgftsreegdlgpvygfqwrhfg
akyvdchtdysgqgvdqlaevirqikeqpdsrriimsawnpsdlgqmvlppchtmcqfyv
dngelscqlyqrsgdmglgvpfnlasygllthmiakvcglkpgtlvhtlgdahvysnhvd
alkiqldrepyafpkirftrdvasiddftsdmialddykchpkipmd

Sequence, based on observed residues (ATOM records):

>d5nood_ d.117.1.0 (D:) automated matches {Nematode (Caenorhabditis elegans) [TaxId: 6239]}
hlnqdeykylkqveqilregtrrddtgtgtisifgmqskyclrngtipllttkrvywkgv
leellwfisgstdgkllmeknvkiwekngdrafldnlgftsreegdlgpvygfqwrhfga
kyvdchtdysgqgvdqlaevirqikeqpdsrriimsawnpsdlgqmvlppchtmcqfyvd
ngelscqlyqrsgdmglgvpfnlasygllthmiakvcglkpgtlvhtlgdahvysnhvda
lkiqldrepyafpkirftrdvasiddftsdmialddykchpkipmd

Timeline for d5nood_:

• d5nood_ first appeared in SCOPe 2.06
  
• d5nood_ appears in SCOPe 2.07