SCOPe 2.06: Domain d5u2bd_: 5u2b D:

Lineage for d5u2bd_ (5u2b D:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (173 PDB entries)

8. Domain d5u2bd_: 5u2b D: [333605]
   automated match to d3q95b_
   complexed with 6wv

Details for d5u2bd_

PDB Entry: 5u2b, 2.22 Å

PDB Description: crystal structure of the er-alpha ligand-binding domain (y537s) in complex with the phenylamino-substituted estrogen, (8r,9s,13s,14s, 17s)-13-methyl-17-(phenylamino)-7,8,9,11,12,13,14,15,16,17-decahydro- 6h-cyclopenta[a]phenanthren-3-ol, without a coactivator peptide

PDB Compounds: (D:) Estrogen receptor

SCOPe Domain Sequences for d5u2bd_:

Sequence, based on SEQRES records:

>d5u2bd_ a.123.1.1 (D:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
nslalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakr
vpgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmve
ifdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkit
dtlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplsdlllem
ldahrlh

Sequence, based on observed residues (ATOM records):

>d5u2bd_ a.123.1.1 (D:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
nslalsltadqmvsalldaeppilyseasmmglltnladrelvhminwakrvpgfvdltl
hdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveifdmllats
srfrmmnlqgeefvclksiillnsgvyeekdhihrvldkitdtlihlmakagltlqqqhq
rlaqlllilshirhmsnkgmehlysmkckvplsdlllemldahrlh

Timeline for d5u2bd_:

• d5u2bd_ is new in SCOPe 2.06-stable
  
• d5u2bd_ appears in SCOPe 2.07
  
• d5u2bd_ appears in the current release, SCOPe 2.08