Lineage for d5up0a_ (5up0 A:)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2342123Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
    multihelical; consists of two different alpha-helical bundles
  4. 2342124Superfamily a.211.1: HD-domain/PDEase-like [109604] (6 families) (S)
  5. 2342214Family a.211.1.2: PDEase [48548] (7 protein domains)
    Pfam PF00233; multihelical; can be divided into three subdomains
  6. 2342501Protein automated matches [190370] (1 species)
    not a true protein
  7. 2342502Species Human (Homo sapiens) [TaxId:9606] [187208] (34 PDB entries)
  8. 2342523Domain d5up0a_: 5up0 A: [333588]
    automated match to d1taza_
    complexed with 8hp, mg, zn

Details for d5up0a_

PDB Entry: 5up0 (more details), 2.04 Å

PDB Description: crystal structure of human pde1b catalytic domain in complex with inhibitor 3 (6-(4-chlorobenzyl)-8,9,10,11-tetrahydrobenzo[4, 5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5(6h)-one)
PDB Compounds: (A:) Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B

SCOPe Domain Sequences for d5up0a_:

Sequence, based on SEQRES records: (download)

>d5up0a_ a.211.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ystavlnclknldlwcfdvfslnqaaddhalrtivfelltrhnlisrfkiptvflmsfld
aletgygkyknpyhnqihaadvtqtvhcfllrtgmvhclseiellaiifaaaihdyehtg
ttnsfhiqtksecaivyndrsvlenhhissvfrlmqddemnifinltkdefvelralvie
mvlatdmschfqqvktmktalqqleridkpkalslllhaadishptkqwlvhsrwtkalm
eeffrqgdkeaelglpfsplcdrtstlvaqsqigfidfiveptfsvltdvaeksvqplad
edsksknqpsfqwrqpsldvevgdpnpdvvsfrstwvkriqenkqkwkeraa

Sequence, based on observed residues (ATOM records): (download)

>d5up0a_ a.211.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ystavlnclknldlwcfdvfslnqaaddhalrtivfelltrhnlisrfkiptvflmsfld
aletgygkyknpyhnqihaadvtqtvhcfllrtgmvhclseiellaiifaaaihdyehtg
ttnsfhiqtksecaivyndrsvlenhhissvfrlmqddemnifinltkdefvelralvie
mvlatdmschfqqvktmktalqqleridkpkalslllhaadishptkqwlvhsrwtkalm
eeffrqgdkeaelglpfsplcdrtstlvaqsqigfidfiveptfsvltdvaeksvpdvvs
frstwvkriqenkqkwkeraa

SCOPe Domain Coordinates for d5up0a_:

Click to download the PDB-style file with coordinates for d5up0a_.
(The format of our PDB-style files is described here.)

Timeline for d5up0a_: