Lineage for d5u2bc_ (5u2b C:)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2335122Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
    multihelical; 3 layers or orthogonally packed helices
  4. 2335123Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families) (S)
  5. 2335124Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 protein domains)
  6. 2335233Protein Estrogen receptor alpha [48519] (1 species)
  7. 2335234Species Human (Homo sapiens) [TaxId:9606] [48520] (71 PDB entries)
    Uniprot P03372 307-551
  8. 2335330Domain d5u2bc_: 5u2b C: [333529]
    automated match to d3q95b_
    complexed with 6wv

Details for d5u2bc_

PDB Entry: 5u2b (more details), 2.22 Å

PDB Description: crystal structure of the er-alpha ligand-binding domain (y537s) in complex with the phenylamino-substituted estrogen, (8r,9s,13s,14s, 17s)-13-methyl-17-(phenylamino)-7,8,9,11,12,13,14,15,16,17-decahydro- 6h-cyclopenta[a]phenanthren-3-ol, without a coactivator peptide
PDB Compounds: (C:) Estrogen receptor

SCOPe Domain Sequences for d5u2bc_:

Sequence, based on SEQRES records: (download)

>d5u2bc_ a.123.1.1 (C:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
rskknslalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhmin
wakrvpgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcve
gmveifdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvl
dkitdtlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplsdl
llemldahrl

Sequence, based on observed residues (ATOM records): (download)

>d5u2bc_ a.123.1.1 (C:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
rskknslalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhmin
wakrvpgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcve
gmveifdmllatssrfrmmnlqgeefvclksiillnsgvytftlksleekdhihrvldki
tdtlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcvplsdlllemld
ahrl

SCOPe Domain Coordinates for d5u2bc_:

Click to download the PDB-style file with coordinates for d5u2bc_.
(The format of our PDB-style files is described here.)

Timeline for d5u2bc_: