SCOPe 2.08: Domain d5frba1: 5frb A:50-518

Lineage for d5frba1 (5frb A:50-518)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.104: Cytochrome P450 [48263] (1 superfamily)
   multihelical

4. Superfamily a.104.1: Cytochrome P450 [48264] (2 families)

5. Family a.104.1.0: automated matches [191509] (1 protein)
   not a true family

6. Protein automated matches [190847] (99 species)
   not a true protein

7. Species Aspergillus fumigatus [TaxId:746128] [276175] (3 PDB entries)

8. Domain d5frba1: 5frb A:50-518 [333382]
   Other proteins in same PDB: d5frba2
   automated match to d3k1oa_
   complexed with hem, vt2

Details for d5frba1

PDB Entry: 5frb, 2.99 Å

PDB Description: crystal structure of sterol 14-alpha demethylase (cyp51b) from a pathogenic filamentous fungus aspergillus fumigatus in complex with a tetrazole-based inhibitor vt-1598

PDB Compounds: (A:) sterol 14-alpha demethylase, cyp51b

SCOPe Domain Sequences for d5frba1:

Sequence; same for both SEQRES and ATOM records:

>d5frba1 a.104.1.0 (A:50-518) automated matches {Aspergillus fumigatus [TaxId: 746128]}
ktppvvfhwfpfigstisygidpykfffdcrakygdiftfillgkkttvylgtkgndfil
ngklrdvcaeevysplttpvfgrhvvydcpnaklmeqkkfvkygltsdalrsyvplitde
vesfvknspafqghkgvfdvcktiaeitiytasrslqgkevrskfdstfaelyhnldmgf
apinfmlpwaplphnrkrdaaqrkltetymeiikarrqagskkdsedmvwnlmscvykng
tpvpdeeiahmmiallmagqhsssstaswivlrlatrpdimeelyqeqirvlgsdlpplt
ydnlqkldlhakviketlrlhapihsiiravknpmavdgtsyviptshnvlsspgvtars
eehfpnplewnphrwdeniaasaeddekvdygyglvskgtnspylpfgagrhrcigeqfa
ylqlgtitavlvrlfrfrnlpgvdgipdtdysslfskplgrsfvefekr

Timeline for d5frba1:

• d5frba1 first appeared in SCOPe 2.06
  
• d5frba1 appears in SCOPe 2.07