SCOPe 2.07: Domain d5t23a1: 5t23 A:146-320

Lineage for d5t23a1 (5t23 A:146-320)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.15: beta-Grasp (ubiquitin-like) [54235] (14 superfamilies)
   core: beta(2)-alpha-beta(2); mixed beta-sheet 2143

4. Superfamily d.15.1: Ubiquitin-like [54236] (11 families)

5. Family d.15.1.5: Ras-binding domain, RBD [54263] (14 proteins)
   contains Pfam PF00788 and Pfam PF02196

6. Protein Phoshoinositide 3-kinase (PI3K) [54274] (2 species)
   includes parts of the flanking linkers

7. Species Human (Homo sapiens) [TaxId:9606] [54276] (77 PDB entries)

8. Domain d5t23a1: 5t23 A:146-320 [333238]
   Other proteins in same PDB: d5t23a2, d5t23a3, d5t23a4
   automated match to d1he8a3
   complexed with 74f

Details for d5t23a1

PDB Entry: 5t23, 2.78 Å

PDB Description: pi3kg in complex with 5d

PDB Compounds: (A:) Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

SCOPe Domain Sequences for d5t23a1:

Sequence, based on SEQRES records:

>d5t23a1 d.15.1.5 (A:146-320) Phoshoinositide 3-kinase (PI3K) {Human (Homo sapiens) [TaxId: 9606]}
esqafqrqltaligydvtdvsnvhddeleftrrglvtprmaevasrdpklyamhpwvtsk
plpeylwkkianncifivihrsttsqtikvspddtpgailqsfftkmakkkslmdipesq
seqdfvlrvcgrdeylvgetpiknfqwvrhclkngeeihvvldtppdpaldevrk

Sequence, based on observed residues (ATOM records):

>d5t23a1 d.15.1.5 (A:146-320) Phoshoinositide 3-kinase (PI3K) {Human (Homo sapiens) [TaxId: 9606]}
esqafqrqltaligydvtdvsnvhddeleftrrglvtprmaevasrdpklyamhpwvtsk
plpeylwkkianncifivihrttsqtikvspddtpgailqdfvlrvcgrdeylvgetpik
nfqwvrhclkngeeihvvldtppdpaldevrk

Timeline for d5t23a1:

• d5t23a1 first appeared in SCOPe 2.06
  
• d5t23a1 appears in the current release, SCOPe 2.08