SCOPe 2.08: Domain d5kykb1: 5kyk B:1-168

Lineage for d5kykb1 (5kyk B:1-168)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (81 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein automated matches [190047] (37 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [186768] (291 PDB entries)

8. Domain d5kykb1: 5kyk B:1-168 [332954]
   Other proteins in same PDB: d5kyka2, d5kykb2, d5kykc2
   automated match to d4obea_
   complexed with 6zd

Details for d5kykb1

PDB Entry: 5kyk, 2.7 Å

PDB Description: covalent gtp-competitive inhibitors of kras g12c: guanosine bisphosphonate analogs

PDB Compounds: (B:) GTPase KRas

SCOPe Domain Sequences for d5kykb1:

Sequence, based on SEQRES records:

>d5kykb1 c.37.1.8 (B:1-168) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mteyklvvvgacgvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildtag
qeeysamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnkcdl
psrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhke

Sequence, based on observed residues (ATOM records):

>d5kykb1 c.37.1.8 (B:1-168) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mteyklvvvgacgvgksaltiqliqnhfvdeyddsyrkqvvidgetclldildtagqerd
qymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnkcdlpsrtvdtkq
aqdlarsygipfietsaktrqgvddafytlvreirkhke

Timeline for d5kykb1:

• d5kykb1 first appeared in SCOPe 2.06
  
• d5kykb1 appears in SCOPe 2.07