SCOPe 2.08: Domain d5uvfc_: 5uvf C:

Lineage for d5uvfc_ (5uvf C:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (37 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1476 PDB entries)

8. Domain d5uvfc_: 5uvf C: [332166]
   automated match to d3op5a_
   complexed with 7dz, cl, peg, po4

Details for d5uvfc_

PDB Entry: 5uvf, 2 Å

PDB Description: crystal structure of the human vaccinia-related kinase bound to bi- d1870

PDB Compounds: (C:) Serine/threonine-protein kinase VRK1

SCOPe Domain Sequences for d5uvfc_:

Sequence, based on SEQRES records:

>d5uvfc_ d.144.1.0 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
favgeiitdmaaaawkvglpigqggfgciyladmnssesvgsdapcvvkvepsdngplft
elkfyqraakpeqiqkwirtrklkylgvpkywgsglhdkngksyrfmimdrfgsdlqkiy
eanakrfsrktvlqlslrildileyiheheyvhgdikasnlllnyknpdqvylvdyglay
rycpegvhkayaadpkrchdgtieftsidahngvapsrrgdleilgycmiqwltghlpwe
dnlkdpkyvrdskiryreniaslmdkcfpaanapgeiakymetvklldytekplyenlrd
illqglkaigskddgkldl

Sequence, based on observed residues (ATOM records):

>d5uvfc_ d.144.1.0 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
favgeiitdmaaaawkvglpigqciyladmndapcvvkvepsgplftelkfyqraakpeq
iqkwirtrklkylgvpkywgsglhsyrfmimdrfgsdlqkiyeanakrfsrktvlqlslr
ildileyiheheyvhgdikasnlllnyknpdqvylvdyglayrycpegvhkayaadpkrc
hdgtieftsidahngvapsrrgdleilgycmiqwltghlpwednlkdpkyvrdskiryre
niaslmdkcfpaanapgeiakymetvklldytekplyenlrdillqglkaigskddgkld
l

Timeline for d5uvfc_:

• d5uvfc_ first appeared in SCOPe 2.06
  
• d5uvfc_ appears in SCOPe 2.07