SCOPe 2.06: Domain d5jv1f_: 5jv1 F:

Lineage for d5jv1f_ (5jv1 F:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.128: Terpenoid synthases [48575] (1 superfamily)
   multihelical; core: 8 helices (C-J) are arranged in 2 parallel layers

4. Superfamily a.128.1: Terpenoid synthases [48576] (6 families)
   duplication: two metal-binding sites are related by a pseudo dyad that also relates helices C-F to helices G-J

5. Family a.128.1.1: Isoprenyl diphosphate synthases [48577] (4 proteins)

6. Protein automated matches [190489] (5 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187688] (78 PDB entries)

8. Domain d5jv1f_: 5jv1 F: [331388]
   automated match to d4demf_
   complexed with so4, yl6

Details for d5jv1f_

PDB Entry: 5jv1, 2.3 Å

PDB Description: crystal structure of human fpps in complex with an allosteric inhibitor cl-08-066

PDB Compounds: (F:) farnesyl pyrophosphate synthase

SCOPe Domain Sequences for d5jv1f_:

Sequence, based on SEQRES records:

>d5jv1f_ a.128.1.1 (F:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vyaqekqdfvqhfsqivrvltedemghpeigdaiarlkevleynaiggkynrgltvvvaf
relveprkqdadslqrawtvgwcvellqafflvaddimdssltrrgqicwyqkpgvglda
indanlleaciyrllklycreqpyylnlielflqssyqteigqtldlltapqgnvdlvrf
tekryksivkyktafysfylpiaaamymagidgekehanakkillemgeffqiqddyldl
fgdpsvtgkigtdiqdnkcswlvvqclqratpeqyqilkenygqkeaekvarvkalyeel
dlpavflqyeedsyshimalieqyaaplppavflglarkiyk

Sequence, based on observed residues (ATOM records):

>d5jv1f_ a.128.1.1 (F:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vyaqekqdfvqhfsqivrvltehpeigdaiarlkevleynaiggkynrgltvvvafrelv
eprkqdadslqrawtvgwcvellqafflvaddimdssltrrgqicwyqkpgvgldainda
nlleaciyrllklycreqpyylnlielflqssyqteigqtldlltapnvdlvrftekryk
sivkyktafysfylpiaaamymagidgekehanakkillemgeffqiqddyldlfgdpsv
tgkigtdiqdnkcswlvvqclqratpeqyqilkenygqkeaekvarvkalyeeldlpavf
lqyeedsyshimalieqyaaplppavflglarkiyk

Timeline for d5jv1f_:

• d5jv1f_ is new in SCOPe 2.06-stable
  
• d5jv1f_ appears in SCOPe 2.07
  
• d5jv1f_ appears in the current release, SCOPe 2.08