SCOPe 2.08: Domain d5uuza1: 5uuz A:1-486

Lineage for d5uuza1 (5uuz A:1-486)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.5: Inosine monophosphate dehydrogenase (IMPDH) [51412] (2 families)
   The phosphate moiety of substrate binds in the 'common' phosphate-binding site

5. Family c.1.5.0: automated matches [227276] (1 protein)
   not a true family

6. Protein automated matches [227084] (16 species)
   not a true protein

7. Species Anthrax bacillus (Bacillus anthracis) [TaxId:1392] [330485] (6 PDB entries)

8. Domain d5uuza1: 5uuz A:1-486 [330917]
   Other proteins in same PDB: d5uuza2, d5uuzb2, d5uuzc2, d5uuzd2, d5uuze2, d5uuzf2, d5uuzg2, d5uuzh2
   automated match to d4q33e_
   complexed with 8l4, imp, k

Details for d5uuza1

PDB Entry: 5uuz, 2.5 Å

PDB Description: crystal structure of the catalytic domain of the inosine monophosphate dehydrogenase from bacillus anthracis in the complex with imp and the inhibitor p200

PDB Compounds: (A:) inosine-5'-monophosphate dehydrogenase

SCOPe Domain Sequences for d5uuza1:

Sequence, based on SEQRES records:

>d5uuza1 c.1.5.0 (A:1-486) automated matches {Anthrax bacillus (Bacillus anthracis) [TaxId: 1392]}
mweskfvkegltfddvllvpaksdvlprevsvktvlseslqlniplisagmdtvteadma
iamarqgglgiihknmsieqqaeqvdkvkrsggllvgaavgvtadamtridalvkasvda
ivldtahghsqgvidkvkevrakypslniiagnvataeatkalieaganvvkvgigpgsi
cttrvvagvgvpqltavydcatearkhgipviadggikysgdmvkalaagahvvmlgsmf
agvaespgeteiyqgrqfkvyrgmgsvgamekgskdryfqegnkklvpegiegrvpykgp
ladtvhqlvgglragmgycgaqdleflrenaqfirmsgaglleshphhvqitkeapnys

Sequence, based on observed residues (ATOM records):

>d5uuza1 c.1.5.0 (A:1-486) automated matches {Anthrax bacillus (Bacillus anthracis) [TaxId: 1392]}
mweskfvkegltfddvllvpaksdvlprevsvktvlseslqlniplisagmdtvteadma
iamarqgglgiihknmsieqqaeqvdkvkrsggllvgaavgvtadamtridalvkasvda
ivldtahghsqgvidkvkevrakypslniiagnvataeatkalieaganvvkvgigpgsi
cttrvvagvgvpqltavydcatearkhgipviadggikysgdmvkalaagahvvmlgsmf
agvaespgeteiyqgrqfkvyrgmgsvgamekvpegiegrvpykgpladtvhqlvgglra
gmgycgaqdleflrenaqfirmsgaglleshphhvqitkeapnys

Timeline for d5uuza1:

• d5uuza1 first appeared in SCOPe 2.06
  
• d5uuza1 appears in SCOPe 2.07