SCOPe 2.08: Domain d5uglb_: 5ugl B:

Lineage for d5uglb_ (5ugl B:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)

8. Domain d5uglb_: 5ugl B: [330259]
   automated match to d4v04b_
   complexed with anp, so4; mutant

Details for d5uglb_

PDB Entry: 5ugl, 1.86 Å

PDB Description: crystal structure of fgf receptor 2 tyrosine kinase domain harboring the d650v activating mutation

PDB Compounds: (B:) Fibroblast growth factor receptor 2

SCOPe Domain Sequences for d5uglb_:

Sequence, based on SEQRES records:

>d5uglb_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
elpedpkwefprdkltlgkplgegafgqvvmaeavgidkdkpkeavtvavkmlkddatek
dlsdlvsememmkmigkhkniinllgactqdgplyviveyaskgnlreylrarrppgmey
sydinrvpeeqmtfkdlvsctyqlargmeylasqkcihrdlaarnvlvtennvmkiadfg
larvinnidyykkttngrlpvkwmapealfdrvythqsdvwsfgvlmweiftlggspypg
ipveelfkllkeghrmdkpanctnelymmmrdcwhavpsqrptfkqlvedldriltlt

Sequence, based on observed residues (ATOM records):

>d5uglb_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
elpedpkwefprdkltlgkplgegafgqvvmaeavgidkdkpkeavtvavkmlkddatek
dlsdlvsememmkmigkhkniinllgactqdgplyviveyaskgnlreylrarrpmtfkd
lvsctyqlargmeylasqkcihrdlaarnvlvtennvmkiadfglarvigrlpvkwmape
alfdrvythqsdvwsfgvlmweiftlggspypgipveelfkllkeghrmdkpanctnely
mmmrdcwhavpsqrptfkqlvedldriltlt

Timeline for d5uglb_:

• d5uglb_ first appeared in SCOPe 2.06
  
• d5uglb_ appears in SCOPe 2.07