Lineage for d5hvba_ (5hvb A:)

  1. Root: SCOPe 2.07
  2. 2434694Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2510888Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 2510889Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) (S)
  5. 2510890Family c.71.1.1: Dihydrofolate reductases [53598] (4 proteins)
  6. 2511215Protein Dihydrofolate reductases, eukaryotic type [53605] (7 species)
  7. 2511263Species Human (Homo sapiens) [TaxId:9606] [53607] (79 PDB entries)
  8. 2511309Domain d5hvba_: 5hvb A: [329195]
    automated match to d1kmva_
    complexed with 65o, ndp

Details for d5hvba_

PDB Entry: 5hvb (more details), 1.6 Å

PDB Description: 5-methyl-6-(1-naphthylthio)thieno[2,3-d]pyrimidine 2,4-diamine
PDB Compounds: (A:) dihydrofolate reductase

SCOPe Domain Sequences for d5hvba_:

Sequence; same for both SEQRES and ATOM records: (download)

>d5hvba_ c.71.1.1 (A:) Dihydrofolate reductases, eukaryotic type {Human (Homo sapiens) [TaxId: 9606]}
vgslncivavsqnmgigkngdlpwpplrnefryfqrmtttssvegkqnlvimgkktwfsi
peknrplkgrinlvlsrelkeppqgahflsrslddalklteqpelankvdmvwivggssv
ykeamnhpghlklfvtrimqdfesdtffpeidlekykllpeypgvlsdvqeekgikykfe
vyeknd

SCOPe Domain Coordinates for d5hvba_:

Click to download the PDB-style file with coordinates for d5hvba_.
(The format of our PDB-style files is described here.)

Timeline for d5hvba_: