SCOPe 2.07: Domain d5wrqb2: 5wrq B:797-1011

Lineage for d5wrqb2 (5wrq B:797-1011)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.166: ADP-ribosylation [56398] (1 superfamily)
   unusual fold

4. Superfamily d.166.1: ADP-ribosylation [56399] (8 families)

5. Family d.166.1.0: automated matches [191650] (1 protein)
   not a true family

6. Protein automated matches [191197] (11 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [225406] (41 PDB entries)

8. Domain d5wrqb2: 5wrq B:797-1011 [329081]
   Other proteins in same PDB: d5wrqa1, d5wrqa3, d5wrqb1, d5wrqb3
   automated match to d4hhyd2
   complexed with 7tx

Details for d5wrqb2

PDB Entry: 5wrq, 2.65 Å

PDB Description: structure of human parp1 catalytic domain bound to a quinazoline-2, 4(1h,3h)-dione inhibitor

PDB Compounds: (B:) Poly [ADP-ribose] polymerase 1

SCOPe Domain Sequences for d5wrqb2:

Sequence; same for both SEQRES and ATOM records:

>d5wrqb2 d.166.1.0 (B:797-1011) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lktdikvvdrdseeaeiirkyvknthatthnaydlevidifkieregecqrykpfkqlhn
rrllwhgsrttnfagilsqglriappeapvtgymfgkgiyfadmvsksanychtsqgdpi
glillgevalgnmyelkhashisklpkgkhsvkglgkttpdpsanisldgvdvplgtgis
sgvndtsllyneyivydiaqvnlkyllklkfnfkt

Timeline for d5wrqb2:

• d5wrqb2 first appeared in SCOPe 2.06