Lineage for d5wrqb1 (5wrq B:662-796)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1998271Fold a.41: Domain of poly(ADP-ribose) polymerase [47586] (1 superfamily)
    core: 4 helices: bundle; unusual topology
  4. 1998272Superfamily a.41.1: Domain of poly(ADP-ribose) polymerase [47587] (2 families) (S)
    duplication: consists of 2 helix-loop-helix structural repeats
    automatically mapped to Pfam PF02877
  5. 1998297Family a.41.1.0: automated matches [227223] (1 protein)
    not a true family
  6. 1998298Protein automated matches [226964] (1 species)
    not a true protein
  7. 1998299Species Human (Homo sapiens) [TaxId:9606] [225405] (44 PDB entries)
  8. 1998368Domain d5wrqb1: 5wrq B:662-796 [329080]
    Other proteins in same PDB: d5wrqa2, d5wrqa3, d5wrqb2, d5wrqb3
    automated match to d4hhyd1
    complexed with 7tx

Details for d5wrqb1

PDB Entry: 5wrq (more details), 2.65 Å

PDB Description: structure of human parp1 catalytic domain bound to a quinazoline-2, 4(1h,3h)-dione inhibitor
PDB Compounds: (B:) Poly [ADP-ribose] polymerase 1

SCOPe Domain Sequences for d5wrqb1:

Sequence, based on SEQRES records: (download)

>d5wrqb1 a.41.1.0 (B:662-796) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ksklpkpvqdlikmifdvesmkkamveyeidlqkmplgklskrqiqaaysilsevqqavs
qgssdsqildlsnrfytliphdfgmkkppllnnadsvqakaemldnlldievaysllrgg
sddsskdpidvnyek

Sequence, based on observed residues (ATOM records): (download)

>d5wrqb1 a.41.1.0 (B:662-796) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ksklpkpvqdlikmifdvesmkkamveyeidlqkmplgklskrqiqaaysilsevqqavs
qgsdsqildlsnrfytliphdfgmkkppllnnadsvqakaemldnlldievaysllrggs
ddsskdpidvnyek

SCOPe Domain Coordinates for d5wrqb1:

Click to download the PDB-style file with coordinates for d5wrqb1.
(The format of our PDB-style files is described here.)

Timeline for d5wrqb1: